Detection of BCR-ABL Transcripts by PCR in IFN-–Treated CML Patients in Cytogenetic Remission
| Study . | N . | Test . | Sensitivity . | Duration of Follow-up* . | PCR+ . | PCR− . | ||
|---|---|---|---|---|---|---|---|---|
| Relapse . | Remission . | Relapse . | Remission . | |||||
| Dhingra et al35 | 18 | One-step PCR | NA | 37.5 (17-91) | 0/15 | 15/15 | 0/3 | 3/3 |
| Opalka et al36 | 30 | Nested PCR | NA | 46 (25-54) | 0/30 | 30/30 | 0/1 | 1/1 |
| Hochhaus et al26 | 20 | Quantitative PCR | NA | 21 (6-69) | 0/20 | 20/20 | — | — |
| Kurzrock et al38 | 18 | Single-step PCR | NA | 87.5 (42-134) | 0/8 | 8/8 | 0/10 | 10/10 |
| Study . | N . | Test . | Sensitivity . | Duration of Follow-up* . | PCR+ . | PCR− . | ||
|---|---|---|---|---|---|---|---|---|
| Relapse . | Remission . | Relapse . | Remission . | |||||
| Dhingra et al35 | 18 | One-step PCR | NA | 37.5 (17-91) | 0/15 | 15/15 | 0/3 | 3/3 |
| Opalka et al36 | 30 | Nested PCR | NA | 46 (25-54) | 0/30 | 30/30 | 0/1 | 1/1 |
| Hochhaus et al26 | 20 | Quantitative PCR | NA | 21 (6-69) | 0/20 | 20/20 | — | — |
| Kurzrock et al38 | 18 | Single-step PCR | NA | 87.5 (42-134) | 0/8 | 8/8 | 0/10 | 10/10 |
Abbreviation: NA, not available.
Months, median (range).