Effect of Jaspamide on Production of Superoxide by Monocytes and HL-60 Cells Incubated in the Absence or Presence of PMA
Treatment . | production (nmol) per 106 Cells During 60 min . | |||
---|---|---|---|---|
Monocytes . | HL-60 Cells . | |||
−PMA . | +PMA . | −PMA . | +PMA . | |
Nil | 3.8 ± 0.3 | 38.3 ± 7.8 | 0 | 1.7 ± 0.35 |
DMSO 0.01% | 5.0 ± 2.0 | 42.3 ± 3.7 | 0 | 1.8 ± 0.05 |
Jaspamide 10−7 mol/L | 3.8 ± 0.1 | 43.1 ± 5.2 | 0 | 2.35 ± 0.4 |
Treatment . | production (nmol) per 106 Cells During 60 min . | |||
---|---|---|---|---|
Monocytes . | HL-60 Cells . | |||
−PMA . | +PMA . | −PMA . | +PMA . | |
Nil | 3.8 ± 0.3 | 38.3 ± 7.8 | 0 | 1.7 ± 0.35 |
DMSO 0.01% | 5.0 ± 2.0 | 42.3 ± 3.7 | 0 | 1.8 ± 0.05 |
Jaspamide 10−7 mol/L | 3.8 ± 0.1 | 43.1 ± 5.2 | 0 | 2.35 ± 0.4 |
production (nmol) per 106 cells during 60 minutes. Results expressed as mean ± SE of 3 experiments performed in quadruplicate.