Table 1.

Frequency of Clinical Prognostic Factors and Immunophenotypes for ALK-Positive and ALK-Negative Groups

Factors ALK+ No. (%)ALK No. (%) P Value
Median age (yr)  30  61  <.002  
Age range (yr)  15-64  27-75  —  
Age ≤60 yr  31 (86) 18 (53)  <.001  
Normal serum LDH  25 (69)  17 (50) .097  
Good performance status  26 (72)  19 (56)  .194 
Stage I or II  17 (47)  12 (35)  .309  
Extranodal sites ≤1  29 (81)  20 (59)  .047  
 B-cell  5 (14) 8 (24)  .256  
 T-cell  15 (42)  17 (50)  .753 
 Null  16 (44)  9 (26)  .246  
 Total  36 (51) 34 (49)  — 
Factors ALK+ No. (%)ALK No. (%) P Value
Median age (yr)  30  61  <.002  
Age range (yr)  15-64  27-75  —  
Age ≤60 yr  31 (86) 18 (53)  <.001  
Normal serum LDH  25 (69)  17 (50) .097  
Good performance status  26 (72)  19 (56)  .194 
Stage I or II  17 (47)  12 (35)  .309  
Extranodal sites ≤1  29 (81)  20 (59)  .047  
 B-cell  5 (14) 8 (24)  .256  
 T-cell  15 (42)  17 (50)  .753 
 Null  16 (44)  9 (26)  .246  
 Total  36 (51) 34 (49)  — 

Abbreviations: LDH, lactate dehydrogenase; good performance status, Eastern Cooperative Oncology Group (ECOG) score <2.

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