Correlation Between CGH Gains and High-Level DNA Amplifications and Gene Amplifications by Southern Blot
| Chromosomal Region . | Gene Examined . | Cases Studied . | Gene Amplification/Gain5-150 . | ||
|---|---|---|---|---|---|
| CGH Amplification . | CGH Gain . | CGH Normal . | |||
| 2pter | N-MYC | 12 | 0/2 | 0/1 | 0/9 |
| 3qter | BCL6 | 30 | 0/6 | 0/13 | 0/11 |
| 8qter | C-MYC | 34 | 1/2 | 0/4 | 0/28 |
| 10p12-p13 | BMI-1 | 9 | 2/2 | — | 0/7 |
| 12q13 | CKD4 | 18 | — | 5/6 | 0/12 |
| 18qter | BCL2 | 18 | 0/4 | 0/4 | 0/10 |
| Chromosomal Region . | Gene Examined . | Cases Studied . | Gene Amplification/Gain5-150 . | ||
|---|---|---|---|---|---|
| CGH Amplification . | CGH Gain . | CGH Normal . | |||
| 2pter | N-MYC | 12 | 0/2 | 0/1 | 0/9 |
| 3qter | BCL6 | 30 | 0/6 | 0/13 | 0/11 |
| 8qter | C-MYC | 34 | 1/2 | 0/4 | 0/28 |
| 10p12-p13 | BMI-1 | 9 | 2/2 | — | 0/7 |
| 12q13 | CKD4 | 18 | — | 5/6 | 0/12 |
| 18qter | BCL2 | 18 | 0/4 | 0/4 | 0/10 |
Number of tumors with gene amplification or gains/number of tumors examined by Southern blot. Not all cases examined by CGH could be analyzed molecularly.