Table 4.

Levels of Plasma VWF:Ag for Each −1234C/T, −1185A/G, and −1051G/A Genotype

Genotype n (%) Mean VWF:Ag Level (SD) (U/mL)P Value4-150
All subjects (n = 250)  
 1/1 33 (13.2)  0.962 (0.443)  
 1/2  111 (44.4) 0.867 (0.354)  .008/.006  
 2/2  106 (42.4) 0.776 (0.407)  
Subjects >40 yrs of age (n = 131) 
 1/1  17 (13.0)  1.075 (0.498)  
 1/2  57 (43.5) 0.954 (0.355)  .003/.001  
 2/2  57 (43.5) 0.794 (0.467)  
Subjects ≤40 yrs of age (n = 112) 
 1/1  14 (12.5)  0.875 (0.358)  
 1/2  52 (46.4) 0.768 (0.336)  .438/.427  
 2/2  46 (41.1) 0.754 (0.338) 
Genotype n (%) Mean VWF:Ag Level (SD) (U/mL)P Value4-150
All subjects (n = 250)  
 1/1 33 (13.2)  0.962 (0.443)  
 1/2  111 (44.4) 0.867 (0.354)  .008/.006  
 2/2  106 (42.4) 0.776 (0.407)  
Subjects >40 yrs of age (n = 131) 
 1/1  17 (13.0)  1.075 (0.498)  
 1/2  57 (43.5) 0.954 (0.355)  .003/.001  
 2/2  57 (43.5) 0.794 (0.467)  
Subjects ≤40 yrs of age (n = 112) 
 1/1  14 (12.5)  0.875 (0.358)  
 1/2  52 (46.4) 0.768 (0.336)  .438/.427  
 2/2  46 (41.1) 0.754 (0.338) 

Haplotype 1: −1234C/−1185A/−1051G. Haplotype 2: −1234T/−1185G/−1051A.

F4-150

ANCOVA (ANOVA)/Kruskal-Wallis test.

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