Table 2. Differentiative Potentials of... | American Society of Hematology

Table 2.

Differentiative Potentials of Mast Cell–Containing Colony-Forming Cells Supported by SCF Plus TPO

CD38/c-kit	Stimuli	Colony Type							Total
CD38/c-kit	Stimuli	n	nm	mast	nmast	nmmast	nmmastE	nmE	Total
+/+	SCF + TPO	0	0	0	3	4	0	0	7
	SCF + FL	1	4	0	1	1	0	0	7
	TPO + FL	0	0	0	0	0	0	0	0
	SCF + TPO + FL	4	1	0	1	5	0	0	11
−/+	SCF + TPO	0	4	0	0	13	1	0	18
	SCF + FL	0	5	0	0	3	0	0	8
	TPO + FL	0	14	0	0	1	0	0	15
	SCF + TPO + FL	0	8	0	0	4	7	12	31
+/−	SCF + TPO	0	0	0	0	0	0	0	0
	SCF + FL	0	0	0	0	0	0	0	0
	TPO + FL	0	0	0	0	0	0	0	0
	SCF + TPO + FL	0	0	0	0	0	0	0	0
−/−	SCF + TPO	0	0	0	0	0	0	0	0
	SCF + FL	0	0	0	0	0	0	0	0
	TPO + FL	0	0	0	0	0	0	0	0
	SCF + TPO + FL	0	1	0	0	0	0	0	1

CD38/c-kit	Stimuli	Colony Type							Total
CD38/c-kit	Stimuli	n	nm	mast	nmast	nmmast	nmmastE	nmE	Total
+/+	SCF + TPO	0	0	0	3	4	0	0	7
	SCF + FL	1	4	0	1	1	0	0	7
	TPO + FL	0	0	0	0	0	0	0	0
	SCF + TPO + FL	4	1	0	1	5	0	0	11
−/+	SCF + TPO	0	4	0	0	13	1	0	18
	SCF + FL	0	5	0	0	3	0	0	8
	TPO + FL	0	14	0	0	1	0	0	15
	SCF + TPO + FL	0	8	0	0	4	7	12	31
+/−	SCF + TPO	0	0	0	0	0	0	0	0
	SCF + FL	0	0	0	0	0	0	0	0
	TPO + FL	0	0	0	0	0	0	0	0
	SCF + TPO + FL	0	0	0	0	0	0	0	0
−/−	SCF + TPO	0	0	0	0	0	0	0	0
	SCF + FL	0	0	0	0	0	0	0	0
	TPO + FL	0	0	0	0	0	0	0	0
	SCF + TPO + FL	0	1	0	0	0	0	0	1

To assess the differentiative potentials of mast cell–containing colony-forming cells supported by various types of growth factor combinations, a two-step culture assay was performed as described in Materials and Methods.

Abbreviations: n, neutrophil; m, macrophage; mast, mast cell; E, erythrocyte.

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