Methylation of DAP-Kinase in Hematologic Malignancies and Normal Cells
| Cell Type . | No. With Aberrant Methylation . | No. of Total Samples . |
|---|---|---|
| Non-cancer cell types | ||
| Normal lymphocytes | 0 | 7 |
| Lymphoblastoid cell lines | 0 | 12 |
| Lymphomas | ||
| Burkitt’s lymphoma cell line (Raji) | 1 | 1 |
| Burkitt’s lymphoma samples | 9 | 9 |
| B-cell lymphoma samples | 21 | 25 |
| T-cell lymphoma samples | 0 | 4 |
| Hodgkin’s lymphoma samples | 2 | 3 |
| Lymphoma samples (unknown cell type) | 9 | 12 |
| Leukemias | ||
| Leukemia cell lines (HL60, KG1a, U937, Jurkat, A3.01) | 3 | 5 |
| B-cell ALL samples | 3 | 20 |
| T-cell ALL samples | 0 | 10 |
| CLL samples | 1 | 11 |
| Pediatric AML samples | 1 | 26 |
| Adult AML samples | 2 | 6 |
| CML samples | 1 | 13 |
| Cell Type . | No. With Aberrant Methylation . | No. of Total Samples . |
|---|---|---|
| Non-cancer cell types | ||
| Normal lymphocytes | 0 | 7 |
| Lymphoblastoid cell lines | 0 | 12 |
| Lymphomas | ||
| Burkitt’s lymphoma cell line (Raji) | 1 | 1 |
| Burkitt’s lymphoma samples | 9 | 9 |
| B-cell lymphoma samples | 21 | 25 |
| T-cell lymphoma samples | 0 | 4 |
| Hodgkin’s lymphoma samples | 2 | 3 |
| Lymphoma samples (unknown cell type) | 9 | 12 |
| Leukemias | ||
| Leukemia cell lines (HL60, KG1a, U937, Jurkat, A3.01) | 3 | 5 |
| B-cell ALL samples | 3 | 20 |
| T-cell ALL samples | 0 | 10 |
| CLL samples | 1 | 11 |
| Pediatric AML samples | 1 | 26 |
| Adult AML samples | 2 | 6 |
| CML samples | 1 | 13 |