Proportional Hazards General Linear Model of Potential Influencial Factors of Molecular Relapse of CML After Allogeneic BMT or PBSCT
| Factors3-150 . | Univariate3-151 . | Multivariate3-152 . | RR (95% CI) . |
|---|---|---|---|
| Patient age | 0.396 | 0.286 | — |
| Donor age | 0.013 | 0.090 | — |
| Interval diagnosis to transplant | 0.015 | 0.071 | — |
| Interferon-α pretransplant | 0.964 | 0.770 | — |
| Nucleated cell dose | 0.034 | 0.495 | — |
| CD34+ cell dose | 0.059 | 0.522 | — |
| Type of donor | 0.348 | 0.973 | — |
| Donor-recipient gender combination | 0.418 | 0.431 | — |
| Acute GVHD | 0.119 | 0.244 | — |
| Chronic GVHD | 0.083 | 0.052 | — |
| Stem cell source | 0.008 | 0.019 | 5.7 (1.3-24.3) |
| Factors3-150 . | Univariate3-151 . | Multivariate3-152 . | RR (95% CI) . |
|---|---|---|---|
| Patient age | 0.396 | 0.286 | — |
| Donor age | 0.013 | 0.090 | — |
| Interval diagnosis to transplant | 0.015 | 0.071 | — |
| Interferon-α pretransplant | 0.964 | 0.770 | — |
| Nucleated cell dose | 0.034 | 0.495 | — |
| CD34+ cell dose | 0.059 | 0.522 | — |
| Type of donor | 0.348 | 0.973 | — |
| Donor-recipient gender combination | 0.418 | 0.431 | — |
| Acute GVHD | 0.119 | 0.244 | — |
| Chronic GVHD | 0.083 | 0.052 | — |
| Stem cell source | 0.008 | 0.019 | 5.7 (1.3-24.3) |
Factors were stratified according to the definitions given in the Materials and Methods section.
Significances derived by log-rank test of event distribution functions across stratified factors.
Significances, relative risk (RR) estimates, and their 95% confidence intervals (CI) derived from proportional hazards general linear model analysis after adjustment for significant factors included in model building.