Table 3.

Significance of Prognostic Variables in Younger and Older CLL Patients

Prognostic VariablesP Value at Univariate (U) and Multivariate (M) Analysis
Younger CLL Patients Older CLL Patients
U M UM
Rai’s stage 0 v I + II v III + IV <.00001  NS  <.00001  <.01    
BM histology: diffuse v nondiffuse  <.05     NS  .01     NS  
Lymphocytes <50 v≥50 × 109/L  <.00001  NS  <.001   NS  
LDT >12 mo v LDT ≤12 mo v AD ≤12 mo <.00001  .00001  <.00001   .0001 
Prognostic VariablesP Value at Univariate (U) and Multivariate (M) Analysis
Younger CLL Patients Older CLL Patients
U M UM
Rai’s stage 0 v I + II v III + IV <.00001  NS  <.00001  <.01    
BM histology: diffuse v nondiffuse  <.05     NS  .01     NS  
Lymphocytes <50 v≥50 × 109/L  <.00001  NS  <.001   NS  
LDT >12 mo v LDT ≤12 mo v AD ≤12 mo <.00001  .00001  <.00001   .0001 

Abbreviation: NS, not significant.

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