Table 1.

Genes Expressed in Hodgkin’s Disease

GenBank Gene NameTemplates HD:Other R(g) 95% Confidence Interval
HD Other
U10687 MAGE-4a  13 1  711  93, 5435  
M77844 Oculorhombin (aniridia PAX6) 5  0  91  22, 381  
AF044197 B-lymphocyte chemoattractant  3  0  383  20, 7411  
L43400 Chromosome 5 P1 clone 792C12  3  0  383  20, 7411 
X86174 SSX1  4  3  73  16, 326  
U54777 MSH6 8  13  34  14, 81  
AF026692 Frizzled-related protein frpHE  9  15  33  14, 75  
U41206 MSH2  0  274  13, 5696  
U83171 Macrophage-derived chemokine (MDC)  19  73  14  9, 24  
U03187 IL-12 receptor 6  19  17  7, 43  
U90582 Chromosome 11p15.5  6  27  7, 109 
GenBank Gene NameTemplates HD:Other R(g) 95% Confidence Interval
HD Other
U10687 MAGE-4a  13 1  711  93, 5435  
M77844 Oculorhombin (aniridia PAX6) 5  0  91  22, 381  
AF044197 B-lymphocyte chemoattractant  3  0  383  20, 7411  
L43400 Chromosome 5 P1 clone 792C12  3  0  383  20, 7411 
X86174 SSX1  4  3  73  16, 326  
U54777 MSH6 8  13  34  14, 81  
AF026692 Frizzled-related protein frpHE  9  15  33  14, 75  
U41206 MSH2  0  274  13, 5696  
U83171 Macrophage-derived chemokine (MDC)  19  73  14  9, 24  
U03187 IL-12 receptor 6  19  17  7, 43  
U90582 Chromosome 11p15.5  6  27  7, 109 

A sample of genes not previously known to be expressed in Hodgkin’s disease selected for Hodgkin’s disease-association [relatively high R(g) values, see text] and biological interest. Templates refer to the number of times a particular sequence was detected in Hodgkin’s disease (HD) and all other human cell sequences (Other). The relative incidence of expression in Hodgkin’s disease as compared with other cells [R(g)] and 95% confidence interval were calculated as described. Genes are ranked in descending order of their lower (L) limit of the 95% confidence interval of the R(g) value. A complete list of the 2,666 distinct genes is deposited on the World Wide Web (www.hodgkins.georgetown.edu, table entitled “Hodgkin’s cells/tissues vs. entire database”).

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