Table 3.

Genes Underrepresented in Hodgkin’s Disease Versus Germinal Center B Cells

GenBank Gene NameTemplates
HD B
U92436 Mutated in multiple advanced cancers protein (MMAC1)  0  29  
X66087 a-myb  0  25  
AF047472 Spleen mitotic checkpoint BUB3 0  18  
M16038 Lyn tyrosine kinase  0  17  
S78085 Programmed cell death-2/Rp8 (PCD2)  0  16  
U34360 Lymphoid nuclear protein (LAF-4)  0  15  
X52056 spi-1 proto-oncogene  0  12  
L04288 Cyclophillin-related protein 0  11  
D14540 Mixed lineage leukemia (MLL)  0  10 
J03779 Common acute lymphoblastic leukemia antigen (CALLA) 0  10  
L78132 Prostate cancer tumor antigen (pcta-1) 0  10  
M27866 Retinoblastoma protein (Rb)  0  10 
S75217 CD79A  0  4  
M89957 CD79B  0  
D83597 RP105 signaling molecule  0  8  
M28170 CD19 0  8  
S76617 Blk  0  9  
U07349 Germinal center kinase  0  
GenBank Gene NameTemplates
HD B
U92436 Mutated in multiple advanced cancers protein (MMAC1)  0  29  
X66087 a-myb  0  25  
AF047472 Spleen mitotic checkpoint BUB3 0  18  
M16038 Lyn tyrosine kinase  0  17  
S78085 Programmed cell death-2/Rp8 (PCD2)  0  16  
U34360 Lymphoid nuclear protein (LAF-4)  0  15  
X52056 spi-1 proto-oncogene  0  12  
L04288 Cyclophillin-related protein 0  11  
D14540 Mixed lineage leukemia (MLL)  0  10 
J03779 Common acute lymphoblastic leukemia antigen (CALLA) 0  10  
L78132 Prostate cancer tumor antigen (pcta-1) 0  10  
M27866 Retinoblastoma protein (Rb)  0  10 
S75217 CD79A  0  4  
M89957 CD79B  0  
D83597 RP105 signaling molecule  0  8  
M28170 CD19 0  8  
S76617 Blk  0  9  
U07349 Germinal center kinase  0  

Examples of genes whose expression was not detected in Hodgkin’s cells and cell lines but were expressed by GBC. The number of encounters is given as templates for Hodgkin’s disease (HD: single cells, cell lines) and GBC (B). Genes listed here are found in the table “Hodgkin’s cells vs. germinal center B cells,” which can be seen at the website given above (see legend for Table 2).

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