Phenotype, Genotype, and Karyotype of Patient Group A (infants)
| Patient No. . | Age (mo) . | Diagnosis . | mllGAAn Genotype . | Karyotype . | |
|---|---|---|---|---|---|
| P . | R . | ||||
| A1 | 4 | AML M7 | bc | bc | 46,XY[8]/46,Y,t(X;6)(p11.2;q23)[22] |
| A2 | 7 | Null ALL | ab | ab | 46,XY,t(11;19)(q23;p13)[10] |
| A3 | 4 | Null ALL | ab | ab | 46,XX[6]/46,XX,t(4;11)(q21;q23)[2] |
| A4 | 14 | ALL | ab | ab | 46,XX[1]/47,XX,+der(8)[3] / 49,XX,+der(8)+der(8) +der(8)[3]/50,XX, +der(8)+der(8)+der(8)+der(8)[2] |
| A5 | 3 | AML M5 | ab | ab | 46,XX [13]/46,XX,t(10;11)p11;q23)[6] |
| A6 | 8 | Pre-B ALL | ab | ab | 46,XX[5]/46,XX,t(9;11)(p21;q23)[15] |
| A7 | 15 | Pre-B ALL | ab | ab | 46,XY,der(1)t(1;19)(q23;p13)[2]/ 48,XY,idem+2+4[1] |
| A8 | 2 | Null ALL | bb | bb | 46,XY [2]/46,XY,t(4;11)(q21;q23)[8] |
| A9 | 7 | Null ALL | aa | aa | 46,XX[1]/46,XX,t(4;11)(q21;q23)[3] |
| A10 | 11 | Null ALL | ab | ab | 46,XY[10]/48,XY,t(11;19;?)(q23;p13;?),+21[5] |
| A11 | 10 | Null ALL | ab | ab | Not done |
| A12 | 12 | T-ALL | ab | ab | 48,XX,+19,+21[3]/49XX,+8,+19,+21[8] |
| A13 | 17 | ALL | ab | ab | 46,XX[1]/46,XX,t(1;19)(q23;p13)[9] |
| A14 | 7 | ALL | ab | ab | 46,XY[1]/46,XY,−5,del(17)(p11),−20,+mar,+mar[8] |
| A15 | 15 | ALL | ab | aa | 46,XY[2]/53,XY,+4,+9,+12,+13,+18,+21,+22[2] |
| A16 | U | U | ab | ab | 46,XY,t(11;17)(q23;p13) |
| A17 | U | U | aa | aa | 46,XY,t(4;11)(q?25;q23) |
| A18 | 8 | AML M2 | ab | ab | 46,XY[4]/46,XY,del(8)(q13q22)[10] |
| Patient No. . | Age (mo) . | Diagnosis . | mllGAAn Genotype . | Karyotype . | |
|---|---|---|---|---|---|
| P . | R . | ||||
| A1 | 4 | AML M7 | bc | bc | 46,XY[8]/46,Y,t(X;6)(p11.2;q23)[22] |
| A2 | 7 | Null ALL | ab | ab | 46,XY,t(11;19)(q23;p13)[10] |
| A3 | 4 | Null ALL | ab | ab | 46,XX[6]/46,XX,t(4;11)(q21;q23)[2] |
| A4 | 14 | ALL | ab | ab | 46,XX[1]/47,XX,+der(8)[3] / 49,XX,+der(8)+der(8) +der(8)[3]/50,XX, +der(8)+der(8)+der(8)+der(8)[2] |
| A5 | 3 | AML M5 | ab | ab | 46,XX [13]/46,XX,t(10;11)p11;q23)[6] |
| A6 | 8 | Pre-B ALL | ab | ab | 46,XX[5]/46,XX,t(9;11)(p21;q23)[15] |
| A7 | 15 | Pre-B ALL | ab | ab | 46,XY,der(1)t(1;19)(q23;p13)[2]/ 48,XY,idem+2+4[1] |
| A8 | 2 | Null ALL | bb | bb | 46,XY [2]/46,XY,t(4;11)(q21;q23)[8] |
| A9 | 7 | Null ALL | aa | aa | 46,XX[1]/46,XX,t(4;11)(q21;q23)[3] |
| A10 | 11 | Null ALL | ab | ab | 46,XY[10]/48,XY,t(11;19;?)(q23;p13;?),+21[5] |
| A11 | 10 | Null ALL | ab | ab | Not done |
| A12 | 12 | T-ALL | ab | ab | 48,XX,+19,+21[3]/49XX,+8,+19,+21[8] |
| A13 | 17 | ALL | ab | ab | 46,XX[1]/46,XX,t(1;19)(q23;p13)[9] |
| A14 | 7 | ALL | ab | ab | 46,XY[1]/46,XY,−5,del(17)(p11),−20,+mar,+mar[8] |
| A15 | 15 | ALL | ab | aa | 46,XY[2]/53,XY,+4,+9,+12,+13,+18,+21,+22[2] |
| A16 | U | U | ab | ab | 46,XY,t(11;17)(q23;p13) |
| A17 | U | U | aa | aa | 46,XY,t(4;11)(q?25;q23) |
| A18 | 8 | AML M2 | ab | ab | 46,XY[4]/46,XY,del(8)(q13q22)[10] |
Abbreviations: P, presentation sample; R, remission sample; U, unknown.