Table 2. Normalized Ratio of APCR... | American Society of Hematology

Table 2.

Normalized Ratio of APCR Measured by Different Assays

Assay	Patient’s Samples^*			Homozygous FV Q506 Individual	Normal Samples
Assay	(1993)	(1995)	(1998)	Homozygous FV Q506 Individual	Normal Samples
Chromogenix-Coatest
No dilution	0.50	ND	0.52	0.50	>0.72
1:5 dilution in Vdp	ND	0.56	0.80	0.44	>0.70
1:10 dilution in Vdp	0.82	0.77	ND	ND	>0.72
Gradipore-PCl
No dilution	ND	ND	0.52	0.43	>0.73
1:5 dilution in Vdp	ND	0.50	0.75	0.45	>0.80
Gradipore-FV Leiden
No dilution	ND	ND	0.34	0.26	ND
1:5 dilution in Vdp	ND	ND	0.79	0.33	ND
1:10 dilution in Vdp	ND	ND	0.84	0.33	ND
Behring-ProC Global
No dilution	ND	0.50	0.41	0.38	ND
1:5 dilution in Vdp	ND	ND	0.81	0.44	ND
1:10 dilution in Vdp	ND	ND	0.87	0.50	ND

Assay	Patient’s Samples^*			Homozygous FV Q506 Individual	Normal Samples
Assay	(1993)	(1995)	(1998)	Homozygous FV Q506 Individual	Normal Samples
Chromogenix-Coatest
No dilution	0.50	ND	0.52	0.50	>0.72
1:5 dilution in Vdp	ND	0.56	0.80	0.44	>0.70
1:10 dilution in Vdp	0.82	0.77	ND	ND	>0.72
Gradipore-PCl
No dilution	ND	ND	0.52	0.43	>0.73
1:5 dilution in Vdp	ND	0.50	0.75	0.45	>0.80
Gradipore-FV Leiden
No dilution	ND	ND	0.34	0.26	ND
1:5 dilution in Vdp	ND	ND	0.79	0.33	ND
1:10 dilution in Vdp	ND	ND	0.84	0.33	ND
Behring-ProC Global
No dilution	ND	0.50	0.41	0.38	ND
1:5 dilution in Vdp	ND	ND	0.81	0.44	ND
1:10 dilution in Vdp	ND	ND	0.87	0.50	ND

Abbreviations: ND, not done; Vdp, Factor V deficient plasma.

All samples were taken when patient received enoxaparine. Baseline clotting times (without APC) were within normal range in all assay systems.