Table 2.

Kinetic Parameters for Hydrolysis of S-2222 by Trocarin and Factor Xa

EnzymeVmax (Δabs/min/μg) Km (mol/L)
Trocarin  0.0055  2.5 × 10−4 
Bovine FXa 7.8  3.1 × 10−4 
Human FXa  4.5 4.0 × 10−4 
EnzymeVmax (Δabs/min/μg) Km (mol/L)
Trocarin  0.0055  2.5 × 10−4 
Bovine FXa 7.8  3.1 × 10−4 
Human FXa  4.5 4.0 × 10−4 
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