Multivariate Analysis by Cox’s Proportional Hazards Model on Intermediate- and High-Grade Non-Hodgkin’s Lymphoma
| Category . | Estimate Value ± SE . | P Value . | Hazards Ratio . |
|---|---|---|---|
| Overall survival | |||
| nm23-H1(<80/≥80 ng/mL) | 1.96 ± 0.39 | .0001 | 7.087 |
| Age (<60/≥60 yr) | 1.35 ± 0.49 | .0053 | 3.877 |
| Performance status (0, 1/2 ∼ 4) | 1.05 ± 0.54 | .0511 | 2.847 |
| Immunophenotype (T/B) | 0.42 ± 0.43 | .3293 | 1.519 |
| Soluble CD44 (<1,000/≥1,000 ng/mL) | 0.39 ± 0.49 | .4278 | 1.473 |
| IPI (L, L-I/H-I, H) | 0.18 ± 0.53 | .7394 | 1.192 |
| Soluble IL-2 receptor (<1,000/≥1,000 U/mL) | 0.18 ± 0.53 | .7394 | 1.192 |
| LDH (normal/>normal) | 0.12 ± 0.62 | .8428 | 1.132 |
| PFS | |||
| nm23-H1 (<80/≥80 ng/mL) | 1.48 ± 0.33 | .0001 | 4.400 |
| Age (<60/≥60 yr) | 0.67 ± 0.38 | .0753 | 1.955 |
| Performance status (0, 1/2 ∼ 4) | 1.52 ± 0.43 | .0004 | 4.573 |
| Immunophenotype (T/B) | 0.37 ± 0.33 | .2710 | 0.693 |
| IPI (L, L-I/H-I, H) | 0.35 ± 0.45 | .4432 | 0.707 |
| Soluble IL-2 receptor (<1,000/≥1,000 U/mL) | 0.17 ± 0.36 | .6408 | 1.185 |
| LDH (normal/>normal) | 0.58 ± 0.48 | .2244 | 1.793 |
| Category . | Estimate Value ± SE . | P Value . | Hazards Ratio . |
|---|---|---|---|
| Overall survival | |||
| nm23-H1(<80/≥80 ng/mL) | 1.96 ± 0.39 | .0001 | 7.087 |
| Age (<60/≥60 yr) | 1.35 ± 0.49 | .0053 | 3.877 |
| Performance status (0, 1/2 ∼ 4) | 1.05 ± 0.54 | .0511 | 2.847 |
| Immunophenotype (T/B) | 0.42 ± 0.43 | .3293 | 1.519 |
| Soluble CD44 (<1,000/≥1,000 ng/mL) | 0.39 ± 0.49 | .4278 | 1.473 |
| IPI (L, L-I/H-I, H) | 0.18 ± 0.53 | .7394 | 1.192 |
| Soluble IL-2 receptor (<1,000/≥1,000 U/mL) | 0.18 ± 0.53 | .7394 | 1.192 |
| LDH (normal/>normal) | 0.12 ± 0.62 | .8428 | 1.132 |
| PFS | |||
| nm23-H1 (<80/≥80 ng/mL) | 1.48 ± 0.33 | .0001 | 4.400 |
| Age (<60/≥60 yr) | 0.67 ± 0.38 | .0753 | 1.955 |
| Performance status (0, 1/2 ∼ 4) | 1.52 ± 0.43 | .0004 | 4.573 |
| Immunophenotype (T/B) | 0.37 ± 0.33 | .2710 | 0.693 |
| IPI (L, L-I/H-I, H) | 0.35 ± 0.45 | .4432 | 0.707 |
| Soluble IL-2 receptor (<1,000/≥1,000 U/mL) | 0.17 ± 0.36 | .6408 | 1.185 |
| LDH (normal/>normal) | 0.58 ± 0.48 | .2244 | 1.793 |