Adenoviruses Used to Infect CLL Cells
| Virus . | E1A . | E1B19K . | E1B55K . | DBP . |
|---|---|---|---|---|
| Ad5dl309 | + | + | + | + |
| E1A− | − | + | + | + |
| Pac3 | − | − | − | + |
| Ad5dl337 | + | − | + | + |
| Ad5ts125 | + | + | + | ts |
| Virus . | E1A . | E1B19K . | E1B55K . | DBP . |
|---|---|---|---|---|
| Ad5dl309 | + | + | + | + |
| E1A− | − | + | + | + |
| Pac3 | − | − | − | + |
| Ad5dl337 | + | − | + | + |
| Ad5ts125 | + | + | + | ts |
The panel of adenovirus mutants used to infect CLL cells. Functional domains of the viruses studied. E1A, wild-type E1A; E1B 55K, E1B encoded 55K polypeptide; E1B 19K, functional E1B encoded 19K polypeptide; E1B encoded 55K polypeptide. None of the viruses have a functional E3 gene. +, wild-type; −, mutated.
Abbreviations: DBP, DNA binding protein; +s, temperature sensitive.