Table 3.

Adenovirus Titers After Infection of CLL Cells

VirusTiter Day 3 Titer Day 6 Titer Day 9
Ad5dl309 4.3 × 105 3.2 × 105 1.3 × 105 
Ad5dl337 5.6 × 105 2.3 × 105 7.8 × 104 
Pac3  3.2 × 105 2.4 × 105 1.8 × 105 
VirusTiter Day 3 Titer Day 6 Titer Day 9
Ad5dl309 4.3 × 105 3.2 × 105 1.3 × 105 
Ad5dl337 5.6 × 105 2.3 × 105 7.8 × 104 
Pac3  3.2 × 105 2.4 × 105 1.8 × 105 

Comparable levels of viral production occur after infection of primary CLL cells with Ad5dl309, Ad5dl337 or Pac3. CLL cells from patient 8 were infected with Ad5dl309, Ad5dl337, or Pac3. Supernatants from the indicated infections were obtained 3, 6, and 9 days after infection and titered. Assays were undertaken on 293 cells.

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