Table 2.

Autologous Stem Cell Transplantation

Drug Dose Day
−8−7 −6 −5 −4 −3 −2 −1 0
Busulfan (orally)  120 mg/m2* x  x  x  
Etoposide (IV 4 h)  300 mg/m2  x  x  
Cyclophosphamide  (IV 1 h)  1500 mg/m2     x  x  x  
Stem cell transfusion          
Drug Dose Day
−8−7 −6 −5 −4 −3 −2 −1 0
Busulfan (orally)  120 mg/m2* x  x  x  
Etoposide (IV 4 h)  300 mg/m2  x  x  
Cyclophosphamide  (IV 1 h)  1500 mg/m2     x  x  x  
Stem cell transfusion          
*

In 4 divided doses per day.

In CNS+ patients, thiotepa at 300 mg/m2/d was administered instead of cyclophosphamide. In this case, transfusion of stem cells was performed 48 hours after the third dose of thiotepa.

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