Table 1.

Prognostic Factors in Univariate Analyses

Factor N 5-yr Survival (%) P
Age at diagnosis (yr)  
 ≤60  85  67  <.0001  
 >60 75  41  
WHO performance status  
 0-1  132  63 <.0001  
 2-4  28  14  
Serum LDH at diagnosis 
 Normal  115  64  <.0001  
 Abnormal  45  33 
Ann Arbor stage  
 I-II  95  66  .0001 
 III-IV  65  37  
Presence of B-symptoms  
 No 130  61  .0001  
 Yes  30  23  
No. of extranodal sites  
 0-1  143  59  .0036  
 >1  17  29 
Histologic grade  
 Low  38  68  .0067 
 Intermediate or high  118  52  
S-bFGF at diagnosis 
 <5.5 pg/mL  120  60  .019  
 ≥5.5 pg/mL (the highest quartile)  40  39  
 <4.8 pg/mL  107  60 .068  
 ≥4.8 pg/mL (the highest tertile)  53  44 
 <3.3 5 pg/mL  80  61  .072  
 ≥3.3 pg/mL (median) 80  49 
Factor N 5-yr Survival (%) P
Age at diagnosis (yr)  
 ≤60  85  67  <.0001  
 >60 75  41  
WHO performance status  
 0-1  132  63 <.0001  
 2-4  28  14  
Serum LDH at diagnosis 
 Normal  115  64  <.0001  
 Abnormal  45  33 
Ann Arbor stage  
 I-II  95  66  .0001 
 III-IV  65  37  
Presence of B-symptoms  
 No 130  61  .0001  
 Yes  30  23  
No. of extranodal sites  
 0-1  143  59  .0036  
 >1  17  29 
Histologic grade  
 Low  38  68  .0067 
 Intermediate or high  118  52  
S-bFGF at diagnosis 
 <5.5 pg/mL  120  60  .019  
 ≥5.5 pg/mL (the highest quartile)  40  39  
 <4.8 pg/mL  107  60 .068  
 ≥4.8 pg/mL (the highest tertile)  53  44 
 <3.3 5 pg/mL  80  61  .072  
 ≥3.3 pg/mL (median) 80  49 
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