Table 4.

Acute GVHD Correlation With Genotype

Genotype aGVHD Grade 0-II aGVHD Grade III-IVP Value
TNFd3/d34-150 27  2 P = .240  
Non-d3/d34-151 80  16  
TNFd3+‡ 81  11  P = .247  
TNFd3−4-153 26  7 
Donor IL-10−1064 
 i(7-11) only  46  7 P = .800  
 i(12-16) present  62  12  
Donor IL-10−1082 
 GG  16  1  P = .670 
 A present  46  7  
 AA  21  3 P = .160  
 G present  41  16  
Recipient IL-10−1064 
 i(7-11) only  49  2 P = .0045  
 i(12-16) present  59  17 
Recipient IL-10−1082 
 GG  28  8 P = .180  
 A present  77  11  
 AA  27 3  P = .561  
 G present  78  16 
Genotype aGVHD Grade 0-II aGVHD Grade III-IVP Value
TNFd3/d34-150 27  2 P = .240  
Non-d3/d34-151 80  16  
TNFd3+‡ 81  11  P = .247  
TNFd3−4-153 26  7 
Donor IL-10−1064 
 i(7-11) only  46  7 P = .800  
 i(12-16) present  62  12  
Donor IL-10−1082 
 GG  16  1  P = .670 
 A present  46  7  
 AA  21  3 P = .160  
 G present  41  16  
Recipient IL-10−1064 
 i(7-11) only  49  2 P = .0045  
 i(12-16) present  59  17 
Recipient IL-10−1082 
 GG  28  8 P = .180  
 A present  77  11  
 AA  27 3  P = .561  
 G present  78  16 
F4-150

TNFd3/d3 homozygotes.

F4-151

TNF genotypes other than d3/d3.

‡

Genotypes with 1 or more TNFd3 allele.

F4-153

Genotypes without a TNFd3 allele.

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