Induction of Apoptosis of Jurkat and JPX-9 Cells by PDTC
| PDTC (μmol/L) . | Jurkat (%) . | JPX-9 (%) . |
|---|---|---|
| 0 | 3.9 ± 0.3 | 4.0 ± 0.3 |
| 1 | 17.9 ± 1.5* | 19.5 ± 1.5* |
| 10 | 39.5 ± 3.0* | 42.8 ± 3.9* |
| 50 | 48.9 ± 4.2* | 54.5 ± 4.0* |
| 100 | 40.5 ± 3.5* | 41.9 ± 2.8* |
| PDTC (μmol/L) . | Jurkat (%) . | JPX-9 (%) . |
|---|---|---|
| 0 | 3.9 ± 0.3 | 4.0 ± 0.3 |
| 1 | 17.9 ± 1.5* | 19.5 ± 1.5* |
| 10 | 39.5 ± 3.0* | 42.8 ± 3.9* |
| 50 | 48.9 ± 4.2* | 54.5 ± 4.0* |
| 100 | 40.5 ± 3.5* | 41.9 ± 2.8* |
Jurkat and JPX-9 cells were incubated with different concentrations of PDTC for 24 hours. After incubation, the percentage of cells with hypodiploid DNA was examined by flow cytometry.
P < .01 compared with control data (absence of PDTC). Data are mean ± SD of 5 experiments.