Adverse Clinical Events Reported During HU Therapy
| Type of Adverse Event . | No. of Events . | No. of Patients . |
|---|---|---|
| Sickle cell-related events | ||
| Vasoocclusive pain | 76 | 34 |
| ACS | 10 | 8 |
| Gallstones | 1 | 1 |
| Priapism | 1 | 1 |
| Splenic sequestration | 1 | 1 |
| Transient ischemic attack | 1 | 1 |
| Other clinical events | ||
| Pain3-150 | 50 | 29 |
| Nausea/vomiting | 25 | 17 |
| Infection | 23 | 20 |
| Headache | 13 | 12 |
| Diarrhea | 7 | 6 |
| Skin rash | 7 | 5 |
| Bleeding | 2 | 1 |
| Growth failure | 0 | 0 |
| Type of Adverse Event . | No. of Events . | No. of Patients . |
|---|---|---|
| Sickle cell-related events | ||
| Vasoocclusive pain | 76 | 34 |
| ACS | 10 | 8 |
| Gallstones | 1 | 1 |
| Priapism | 1 | 1 |
| Splenic sequestration | 1 | 1 |
| Transient ischemic attack | 1 | 1 |
| Other clinical events | ||
| Pain3-150 | 50 | 29 |
| Nausea/vomiting | 25 | 17 |
| Infection | 23 | 20 |
| Headache | 13 | 12 |
| Diarrhea | 7 | 6 |
| Skin rash | 7 | 5 |
| Bleeding | 2 | 1 |
| Growth failure | 0 | 0 |
Pain reported by the patient that was not felt to be related to complications of sickle cell anemia by the patient and staff at participating center.