Table 2.

Percentages of L1210 Cells in Different Phases of the Cell Cycle, After 72 Hours’ Pretreatment With Either a Control Solvent or RA at the Indicated Concentrations, Followed by a 24-Hour PSI or Control Treatment

Cells G0/G1 S G2/M
Control  33.8  11.1 55.1  
RA 5 μmol/L  43.9  11.0  45.1  
RA 50 μmol/L  51.5  7.2  48.3  
PSI 500 nmol/L  49.8  4.5 45.7  
PSI 500 nmol/L RA 5 μmol/L  55.7  2.9  41.4 
PSI 500 nmol/L RA 50 μmol/L  44.9  7.0  48.1 
Cells G0/G1 S G2/M
Control  33.8  11.1 55.1  
RA 5 μmol/L  43.9  11.0  45.1  
RA 50 μmol/L  51.5  7.2  48.3  
PSI 500 nmol/L  49.8  4.5 45.7  
PSI 500 nmol/L RA 5 μmol/L  55.7  2.9  41.4 
PSI 500 nmol/L RA 50 μmol/L  44.9  7.0  48.1 

Data were obtained for the living cells fraction of the same groups as in Table 1. Cell-cycle percentages were calculated depending on the DNA content with the use of CELLQuest v.1.2 software system.

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