Induction of Adhesion Molecules on EC by Tat-MBP
| Antigen . | Endothelial-Cell Treatment* . | |||
|---|---|---|---|---|
| Control . | IL-1 . | Tat-MBP . | MBP . | |
| ICAM-1 | 69 (65)† | 99 (347) | 78 (128) | 79 (84) |
| E-selectin | 4 (55) | 91 (209) | 66 (102) | 7 (56) |
| VCAM-1 | 1 (23) | 45 (26) | 13 (33) | 3 (17) |
| Antigen . | Endothelial-Cell Treatment* . | |||
|---|---|---|---|---|
| Control . | IL-1 . | Tat-MBP . | MBP . | |
| ICAM-1 | 69 (65)† | 99 (347) | 78 (128) | 79 (84) |
| E-selectin | 4 (55) | 91 (209) | 66 (102) | 7 (56) |
| VCAM-1 | 1 (23) | 45 (26) | 13 (33) | 3 (17) |
Results represent one typical experiment out of three performed.
EC were treated for 4 hours with medium (control), IL-1 (2 ng/mL), Tat-MBP (20 ng/mL), or equimolar concentrations of MBP.
Results (determined by FACS analysis) are expressed as the percentage of positive cells and the mean channel of fluorescence intensity.