Differentiation Potential of CD34+c-kit+Cells
Parameter . | Day 11 AGM . | Day 11 Liver . | Adult Bone Marrow . |
---|---|---|---|
Total clones (n) | 94 | 76 | 124 |
Bilineage- or unilineage-restricted (%) | 13 | 71 | 100 |
Multimyeloid (%) | 49 | 9 | 0 |
Multimyeloid + B-cell potential (%) | 38 | 20 | 0 |
Parameter . | Day 11 AGM . | Day 11 Liver . | Adult Bone Marrow . |
---|---|---|---|
Total clones (n) | 94 | 76 | 124 |
Bilineage- or unilineage-restricted (%) | 13 | 71 | 100 |
Multimyeloid (%) | 49 | 9 | 0 |
Multimyeloid + B-cell potential (%) | 38 | 20 | 0 |
Clones developing from single CD34+c-kit+cells isolated from the AGM and fetal liver of day 11 mouse embryos and from the bone marrow of 3-week-old animals were analyzed for the capacity to differentiate into different hematopoientic lineages using the culture system shown in Fig 1B.