Table 1.

Differentiation Potential of CD34+c-kit+Cells

Parameter Day 11 AGM Day 11 Liver Adult Bone Marrow
Total clones (n)  94  76  124 
Bilineage- or unilineage-restricted (%)  13  71  100 
Multimyeloid (%)  49  9  0  
Multimyeloid + B-cell potential (%)  38  20  
Parameter Day 11 AGM Day 11 Liver Adult Bone Marrow
Total clones (n)  94  76  124 
Bilineage- or unilineage-restricted (%)  13  71  100 
Multimyeloid (%)  49  9  0  
Multimyeloid + B-cell potential (%)  38  20  

Clones developing from single CD34+c-kit+cells isolated from the AGM and fetal liver of day 11 mouse embryos and from the bone marrow of 3-week-old animals were analyzed for the capacity to differentiate into different hematopoientic lineages using the culture system shown in Fig 1B.

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