Expression of Certain Neutrophil Characteristics Is Restored in PU.1-Transduced But Not in G-CSF Receptor-Transduced or Parental PU.1-Deficient 503 Cells
| . | Cell Lines . | ||
|---|---|---|---|
| 503 . | 503-PU . | 503-GR . | |
| G-CSF receptor protein & response to G-CSF | − | + | + |
| mNC mRNA | − | + | − |
| mNG mRNA | − | + | − |
| gp91phox mRNA | − | + | − |
| Cytochrome c reduction | − | + | − |
| . | Cell Lines . | ||
|---|---|---|---|
| 503 . | 503-PU . | 503-GR . | |
| G-CSF receptor protein & response to G-CSF | − | + | + |
| mNC mRNA | − | + | − |
| mNG mRNA | − | + | − |
| gp91phox mRNA | − | + | − |
| Cytochrome c reduction | − | + | − |
Abbreviations: mNC, murine neutrophil collagenase; mNG, murine neutrophil gelatinase.