Patients With Disparity for an HLA-DRB1 Allele
| UPN . | No. of CD4 Cells/kg (×10−4) . | No. of CD8 Cells/kg (×10−6) . | Graft Failure . | GVHD Grade . | Survival (d) . | Cause of Death . | |
|---|---|---|---|---|---|---|---|
| Given . | Intended . | ||||||
| 8399 | BL | 13.0 | NA | No | IV | 118 | GVHD |
| 8343 | BL | 9.1 | NA | No | III | 39 | Bacterial infection |
| 8358 | 0.069 | 5.6 | 5.0 | No | III | 68 | Bacterial infection |
| 8634 | BL | 5.0 | 5.0 | No | III | 166 | CMV infection; chronic GVHD |
| 8650 | 0.35 | 4.6 | 5.0 | NE | NE | 4 | Cardiomyopathy |
| 9303 | 3.7 | 4.3 | 5.0 | No | III | 57 | CMV infection |
| 8441 | BL | 3.9 | 5.0 | No | III | 465 | P carinii infection; chronic GVHD |
| 9363 | 0.24 | 3.1 | 5.0 | No | III | 499 | Recurrent malignancy |
| 8670 | 0.49 | 2.8 | 2.5 | No | II | >988 | |
| 9202 | 2.0 | 2.7 | 2.5 | Yes | NE | >956 | |
| 8286 | BL | 2.6 | 5.0 | Yes | NE | 173 | Fungal infection |
| 8532 | 20 | 1.4 | 1.25 | No | I | >1,133 | |
| 8940 | 0.58 | 1.3 | 1.25 | Yes | NE | 26 | Bacterial infection; hemorrhage |
| 8371 | 0.046 | 1.1 | 1.25 | Yes | NE | 508 | Recurrent malignancy |
| UPN . | No. of CD4 Cells/kg (×10−4) . | No. of CD8 Cells/kg (×10−6) . | Graft Failure . | GVHD Grade . | Survival (d) . | Cause of Death . | |
|---|---|---|---|---|---|---|---|
| Given . | Intended . | ||||||
| 8399 | BL | 13.0 | NA | No | IV | 118 | GVHD |
| 8343 | BL | 9.1 | NA | No | III | 39 | Bacterial infection |
| 8358 | 0.069 | 5.6 | 5.0 | No | III | 68 | Bacterial infection |
| 8634 | BL | 5.0 | 5.0 | No | III | 166 | CMV infection; chronic GVHD |
| 8650 | 0.35 | 4.6 | 5.0 | NE | NE | 4 | Cardiomyopathy |
| 9303 | 3.7 | 4.3 | 5.0 | No | III | 57 | CMV infection |
| 8441 | BL | 3.9 | 5.0 | No | III | 465 | P carinii infection; chronic GVHD |
| 9363 | 0.24 | 3.1 | 5.0 | No | III | 499 | Recurrent malignancy |
| 8670 | 0.49 | 2.8 | 2.5 | No | II | >988 | |
| 9202 | 2.0 | 2.7 | 2.5 | Yes | NE | >956 | |
| 8286 | BL | 2.6 | 5.0 | Yes | NE | 173 | Fungal infection |
| 8532 | 20 | 1.4 | 1.25 | No | I | >1,133 | |
| 8940 | 0.58 | 1.3 | 1.25 | Yes | NE | 26 | Bacterial infection; hemorrhage |
| 8371 | 0.046 | 1.1 | 1.25 | Yes | NE | 508 | Recurrent malignancy |
Patients are listed according to the number of CD8 cells in the graft.
Abbreviations: UPN, unique patient number; BL, below limits of detection; NA, not applicable because CD8 cells were not removed from the marrow for these patients; NE, not evaluable for graft failure because of early death, or not evaluable for acute GVHD because donor cells did not engraft.