Table 2.

Patients With Disparity for an HLA-A or -B Antigen

UPN No. of CD4 Cells/kg (×10−4) No. of CD8 Cells/kg (×10−6) Graft Failure GVHD Grade Survival (d) Cause of Death
GivenIntended
8351  BL  17.1  NA  No  II  54 Recurrent malignancy  
8268  0.13  8.7  NA  No  II 180  Chronic GVHD  
7911  21  8.7  NA  No  III 48  Fungal infection  
7850  1.9  5.9  5.0  No II  >896  
9478  BL  5.4  5.0  No III  817  Unknown  
8945  0.59  4.7  5.0  No II  42  Fungal infection  
9994  0.13  4.6  5.0 No  II  243  Recurrent malignancy  
8125  0.45 4.6  NA  NE  NE  12  Fungal infection  
9542 0.30  4.1  5.0  No  II  648  Chronic GVHD 
8553  0.046  3.9  NA  No  III  77  Bacterial infection  
7872  0.61  3.1  2.5  Yes  NE  111 Fungal infection  
8765  1.6  2.4  2.5  No  II 156  Recurrent malignancy  
9022  1.9  2.2  2.5 Yes* IV  67  Bacterial infection 
UPN No. of CD4 Cells/kg (×10−4) No. of CD8 Cells/kg (×10−6) Graft Failure GVHD Grade Survival (d) Cause of Death
GivenIntended
8351  BL  17.1  NA  No  II  54 Recurrent malignancy  
8268  0.13  8.7  NA  No  II 180  Chronic GVHD  
7911  21  8.7  NA  No  III 48  Fungal infection  
7850  1.9  5.9  5.0  No II  >896  
9478  BL  5.4  5.0  No III  817  Unknown  
8945  0.59  4.7  5.0  No II  42  Fungal infection  
9994  0.13  4.6  5.0 No  II  243  Recurrent malignancy  
8125  0.45 4.6  NA  NE  NE  12  Fungal infection  
9542 0.30  4.1  5.0  No  II  648  Chronic GVHD 
8553  0.046  3.9  NA  No  III  77  Bacterial infection  
7872  0.61  3.1  2.5  Yes  NE  111 Fungal infection  
8765  1.6  2.4  2.5  No  II 156  Recurrent malignancy  
9022  1.9  2.2  2.5 Yes* IV  67  Bacterial infection 

Patients are listed according to the number of CD8 cells in the graft.

Abbreviations: UPN, unique patient number; BL, below limits of detection; NA, not applicable because CD8 cells were not removed from the marrow for these patients; NE, not evaluable for graft failure because of early death, or not evaluable for acute GVHD because donor cells did not engraft.

*

This patient had graft failure after initial engraftment.

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