Baseline Characteristics of Patients
| . | Matched (n = 85) . | Mismatched (n = 52) . | P Value . |
|---|---|---|---|
| Age in years, median (range) | 9 (1-17) | 7 (1-15) | .069 |
| Sex of recipient M:F | 57:28 | 30:22 | .356 |
| Sex of donor M:F | 47:37* | 24:28 | .350 |
| Disease status | |||
| CR1 | 15 (17.6%) | 9 (17.3%) | .778† |
| CR2 | 53 (62.4%) | 35 (67.3%) | |
| CR3 | 13 (15.3%) | 5 (9.6%) | |
| CR4 | 2 (2.4%) | 0 (0%) | |
| Not in remission | 2 (2.4%) | 3 (5.8%) | |
| CR1 median days diagnosis to BMT (range) | 201 (63-598) | 191 (138-316) | |
| CR2 median days diagnosis to relapse (range) | 852 (152-2,011) | 823 (198-1,883) | .951 |
| CR2 median days relapse to BMT (range) | 158 (60-651) | 169 (84-368) | |
| CMV status recipient/donor | |||
| Neg/neg | 52 (61.2%) | 24 (46.2%) | .124 |
| Any other | 33 (38.8%) | 28 (53.8%) | |
| TNC harvested (×108/kg), median (range) | 4.0 (1.9-15.0) | 5.6 (2.8-14.8) | .006 |
| No methotrexate | 79 (92.9%) | 15 (28.9%) | <.001 |
| Methotrexate | 6 (7.1%) | 37 (71.1%) |
| . | Matched (n = 85) . | Mismatched (n = 52) . | P Value . |
|---|---|---|---|
| Age in years, median (range) | 9 (1-17) | 7 (1-15) | .069 |
| Sex of recipient M:F | 57:28 | 30:22 | .356 |
| Sex of donor M:F | 47:37* | 24:28 | .350 |
| Disease status | |||
| CR1 | 15 (17.6%) | 9 (17.3%) | .778† |
| CR2 | 53 (62.4%) | 35 (67.3%) | |
| CR3 | 13 (15.3%) | 5 (9.6%) | |
| CR4 | 2 (2.4%) | 0 (0%) | |
| Not in remission | 2 (2.4%) | 3 (5.8%) | |
| CR1 median days diagnosis to BMT (range) | 201 (63-598) | 191 (138-316) | |
| CR2 median days diagnosis to relapse (range) | 852 (152-2,011) | 823 (198-1,883) | .951 |
| CR2 median days relapse to BMT (range) | 158 (60-651) | 169 (84-368) | |
| CMV status recipient/donor | |||
| Neg/neg | 52 (61.2%) | 24 (46.2%) | .124 |
| Any other | 33 (38.8%) | 28 (53.8%) | |
| TNC harvested (×108/kg), median (range) | 4.0 (1.9-15.0) | 5.6 (2.8-14.8) | .006 |
| No methotrexate | 79 (92.9%) | 15 (28.9%) | <.001 |
| Methotrexate | 6 (7.1%) | 37 (71.1%) |