Table 2.

Distribution of Risk Factors for GVHD According to HA-1 Disparity

Risk Factor Recipient HA-1 Disparity P Value
Absent (n = 201)Present (n = 34)
Median age in years (range) 31 (1-65)  36 (2-58)  .56  
Recipient age (n; %)   .71  
 ≤16 yrs  22 (11)  3 (9)  
 >16 yrs 179 (89)  31 (91)  
Transplant year (n; %)    .48 
 Before 1991  148 (74)  27 (79)  
 1991 or later 53 (26)  7 (21)  
Donor/recipient gender (n; %)   .49  
 Male/male  59 (29)  10 (29) 
 Male/female  50 (25)  4 (12)  
 Parous female/female 24 (12)  7 (21)  
 Nulliparous female/female  20 (10) 4 (12)  
 Parous female/male  22 (11)  6 (18) 
 Nulliparous female/male  17 (8)  2 (6)  
 Female, unknown parity* 9 (4)  1 (3)  
Advanced malignancy (n; %)   .03  
 No  153 (76)  20 (59)  
 Yes 48 (24)  14 (41)  
TBI (n; %)    .17  
 ≤12 Gy 81 (40)  13 (38)  
 >12 Gy  54 (27)  14 (41) 
 None  66 (33)  7 (21) 
Risk Factor Recipient HA-1 Disparity P Value
Absent (n = 201)Present (n = 34)
Median age in years (range) 31 (1-65)  36 (2-58)  .56  
Recipient age (n; %)   .71  
 ≤16 yrs  22 (11)  3 (9)  
 >16 yrs 179 (89)  31 (91)  
Transplant year (n; %)    .48 
 Before 1991  148 (74)  27 (79)  
 1991 or later 53 (26)  7 (21)  
Donor/recipient gender (n; %)   .49  
 Male/male  59 (29)  10 (29) 
 Male/female  50 (25)  4 (12)  
 Parous female/female 24 (12)  7 (21)  
 Nulliparous female/female  20 (10) 4 (12)  
 Parous female/male  22 (11)  6 (18) 
 Nulliparous female/male  17 (8)  2 (6)  
 Female, unknown parity* 9 (4)  1 (3)  
Advanced malignancy (n; %)   .03  
 No  153 (76)  20 (59)  
 Yes 48 (24)  14 (41)  
TBI (n; %)    .17  
 ≤12 Gy 81 (40)  13 (38)  
 >12 Gy  54 (27)  14 (41) 
 None  66 (33)  7 (21) 
*

This group included 7 male and 3 female patients.

Patients with hematologic malignancy in relapse, accelerated phase, or blast phase at the time of transplantation.

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