Table 3.

Multivariable Logistic Regression Model of Risk Factors for Grades II-IV Acute GVHD

Risk Factor Odds Ratio 95% CI P Value
Patients age (per decade)3-150 1.47  1.16-1.86  .002 
Transplant year  
 ≥1991  1.0  
 <1991  0.84 0.39-1.81  .65  
Donor/recipient gender  
 Male/male 1.0  
 Male/female  1.69  0.77-3.71  .19  
 Parous female/female  0.94  0.37-2.38  .89  
 Nulliparous female/female  0.92  0.31-2.70  .88  
 Parous female/male 1.90  0.70-5.18  .21  
 Nulliparous female/male  1.34 0.44-4.09  .61  
 Missing parity data  0.96  0.23-4.02 .95  
Advanced malignancy3-151 
 No  1.0  
 Yes 1.86  0.96-3.59  .06  
TBI  
 ≤12 Gy  1.0 
 >12 Gy  2.08  1.03-4.20  .04  
 None  0.52 0.24-1.11  .09  
HA-1 disparity  
 Absent  1.0 
 Present  2.1  0.91-4.68  .08 
Risk Factor Odds Ratio 95% CI P Value
Patients age (per decade)3-150 1.47  1.16-1.86  .002 
Transplant year  
 ≥1991  1.0  
 <1991  0.84 0.39-1.81  .65  
Donor/recipient gender  
 Male/male 1.0  
 Male/female  1.69  0.77-3.71  .19  
 Parous female/female  0.94  0.37-2.38  .89  
 Nulliparous female/female  0.92  0.31-2.70  .88  
 Parous female/male 1.90  0.70-5.18  .21  
 Nulliparous female/male  1.34 0.44-4.09  .61  
 Missing parity data  0.96  0.23-4.02 .95  
Advanced malignancy3-151 
 No  1.0  
 Yes 1.86  0.96-3.59  .06  
TBI  
 ≤12 Gy  1.0 
 >12 Gy  2.08  1.03-4.20  .04  
 None  0.52 0.24-1.11  .09  
HA-1 disparity  
 Absent  1.0 
 Present  2.1  0.91-4.68  .08 
F3-150

Modeled as a continuous variable.

F3-151

Patients with hematologic malignancy in relapse, accelerated phase, or blast phase at the time of transplantation.

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