Evaluation of Erythroid and Nonerythroid Progenitors in Spleens From Normal and Fas-Deficient C57BL/6-lpr/lpr Mice
| . | CFU-GM . | CFU-Mix Per Spleen (×100) . | BFU-E . |
|---|---|---|---|
| C57BL/6-lpr/lpr | 1,017.1 ± 325.0 | 109.3 ± 54.1 | 108.6 ± 38.9 |
| P < .001 | |||
| C57BL/6 | 29.6 ± 5.9 | 2.8 ± 1.9 | 3.0 ± 1.5 |
| . | CFU-GM . | CFU-Mix Per Spleen (×100) . | BFU-E . |
|---|---|---|---|
| C57BL/6-lpr/lpr | 1,017.1 ± 325.0 | 109.3 ± 54.1 | 108.6 ± 38.9 |
| P < .001 | |||
| C57BL/6 | 29.6 ± 5.9 | 2.8 ± 1.9 | 3.0 ± 1.5 |
Total CFU-C were quantified in spleens from 6-month-old mice using MethoCult M3434 medium. Colonies were scored on day 7 to 8 and analyzed for the presence of erythroid cells. Data represent means ± SEM from 3 separate experiments.