Table 1.

Apheresis Product Cell Count

Animal No. PBMNC in Apheresis Product CD34+Cells Immune Selected Yield of CD34+ Cells as of % PBMNC Transduced CD34+ Cells Infused
4657 1.45 × 1010 22.6 × 106 0.155  98 × 106 
4630 2.6 × 1010 12.56 × 106 0.048  (died)  
4694 1.7 × 1010 48.25 × 106 0.28 121 × 106 
4649  1.2 × 1010 11.705 × 106 0.097  70 × 106 
J546  0.84 × 1010 10.9 × 106 0.13  2.5 × 106 
Mean ± SD  1.56 ± 0.66 × 1010 21.2 ± 15.8 × 106 0.142 ± 0.08 73 ± 51.4 × 106 
Animal No. PBMNC in Apheresis Product CD34+Cells Immune Selected Yield of CD34+ Cells as of % PBMNC Transduced CD34+ Cells Infused
4657 1.45 × 1010 22.6 × 106 0.155  98 × 106 
4630 2.6 × 1010 12.56 × 106 0.048  (died)  
4694 1.7 × 1010 48.25 × 106 0.28 121 × 106 
4649  1.2 × 1010 11.705 × 106 0.097  70 × 106 
J546  0.84 × 1010 10.9 × 106 0.13  2.5 × 106 
Mean ± SD  1.56 ± 0.66 × 1010 21.2 ± 15.8 × 106 0.142 ± 0.08 73 ± 51.4 × 106 

CD34+ cells placed in culture after immune selection from the apheresis product, and the number of cells transfused after 4 days of ex vivo culture and transduction.

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