Table 2.

Breast Cancer Biopsy Surface Antigens

Biopsies Dx SLT-R Combined Ber-EP4/M38 LMWK
BC-1  IDC  +/++  +/++  ND  
BC-2  IDC  ++ ++  ND  
BC-3  IDC  +  −  ND  
BC-4  ILC ++  −  ND  
BC-5  IDC  +  −  +  
BC-6 ILC  +  −  +  
BC-7  IDC  ++  ++  
BC-8  IDC  −  −  ND  
BC-9  ILC  − −  ND  
BC-10  IDC  +++  +++  ND 
Biopsies Dx SLT-R Combined Ber-EP4/M38 LMWK
BC-1  IDC  +/++  +/++  ND  
BC-2  IDC  ++ ++  ND  
BC-3  IDC  +  −  ND  
BC-4  ILC ++  −  ND  
BC-5  IDC  +  −  +  
BC-6 ILC  +  −  +  
BC-7  IDC  ++  ++  
BC-8  IDC  −  −  ND  
BC-9  ILC  − −  ND  
BC-10  IDC  +++  +++  ND 

Flow cytometric analysis of primary based cancer biopsy material for surface expression of SLT-R and combined Ber-EP4/M38. Also shown are results for immunohistochemical analysis of cytospins for LMWK. Expression of surface antigen in terms of percentage of cells staining positively for a marker: defined as negative or − (0% to 14%), weak or + (15% to 40%), intermediate or ++ (41% to 70%), and strong or +++ (71% to 100%).

Abbreviations: Dx, morphological diagnosis; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; LMWK, low molecular weight keratins detected by immunohistochemistry, expression is defined as negative (−) or positive (+) only; ND, not determined.

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