Table 1. Clinical Characteristics of 16... | American Society of Hematology

Table 1.

Clinical Characteristics of 16 Pediatric Patients With SCD and Stroke Who Discontinued Chronic Transfusions and Received Oral Hydroxyurea Therapy to Prevent Stroke Recurrence

Patient No.	Hemoglobin Diagnosis	Age at First Stroke (yr)	Type of Stroke	Transfusions		Reasons to Stop Transfusions	Age Transfusions Stopped (yr)
Patient No.	Hemoglobin Diagnosis	Age at First Stroke (yr)	Type of Stroke	mo	Type	Reasons to Stop Transfusions	Age Transfusions Stopped (yr)
1	SS	12.3	R hemiplegia	82	S, E, P	AlloAb, AutoAb, Iron, NC	19.1
2	SS	4.5	R exotropia	47	S, E, P	AutoAb, NC	8.4
3	SS	5.7	L hemiplegia	7	S	AutoAb	6.3
4	SS	7.7	R hemiplegia, aphasia	13	S	2nd stroke on transfusions	8.8
5	SS	6.5	L hemiplegia	72	S, E, P	AlloAb, AutoAb	16.7
6	SS	6.4	R hemiplegia, aphasia	72	S, E, P	Iron, NC	12.3
7	SS	5.3	R hemiplegia, aphasia	37	S, E	Iron	8.4
8	SS	5.5	Coma, seizures	127	S, E, P	Iron, DFO allergy	16.1
9	SS	6.5	R hemiplegia	79	S, P	Iron, NC	13.1
10	SS	8.3	R hand	34	S, E	Iron, NC	11.2
11	SS	17.3	L hemiplegia	28	S, E	NC	19.7
12	SS	3.0	L hemiplegia	54	S	Iron, DFO allergy	7.6
13	SS	15.0	R hemiplegia, aphasia	39	S, E	Iron, NC	18.4
14	SO_Arab	1.1	L hand	22	S	Iron	2.9
15	SS	6.3	R hemiplegia	54	S, E, P	Iron	10.7
16	SS	2.7	L hand	127	S	Iron	13.3

Patient No.	Hemoglobin Diagnosis	Age at First Stroke (yr)	Type of Stroke	Transfusions		Reasons to Stop Transfusions	Age Transfusions Stopped (yr)
Patient No.	Hemoglobin Diagnosis	Age at First Stroke (yr)	Type of Stroke	mo	Type	Reasons to Stop Transfusions	Age Transfusions Stopped (yr)
1	SS	12.3	R hemiplegia	82	S, E, P	AlloAb, AutoAb, Iron, NC	19.1
2	SS	4.5	R exotropia	47	S, E, P	AutoAb, NC	8.4
3	SS	5.7	L hemiplegia	7	S	AutoAb	6.3
4	SS	7.7	R hemiplegia, aphasia	13	S	2nd stroke on transfusions	8.8
5	SS	6.5	L hemiplegia	72	S, E, P	AlloAb, AutoAb	16.7
6	SS	6.4	R hemiplegia, aphasia	72	S, E, P	Iron, NC	12.3
7	SS	5.3	R hemiplegia, aphasia	37	S, E	Iron	8.4
8	SS	5.5	Coma, seizures	127	S, E, P	Iron, DFO allergy	16.1
9	SS	6.5	R hemiplegia	79	S, P	Iron, NC	13.1
10	SS	8.3	R hand	34	S, E	Iron, NC	11.2
11	SS	17.3	L hemiplegia	28	S, E	NC	19.7
12	SS	3.0	L hemiplegia	54	S	Iron, DFO allergy	7.6
13	SS	15.0	R hemiplegia, aphasia	39	S, E	Iron, NC	18.4
14	SO_Arab	1.1	L hand	22	S	Iron	2.9
15	SS	6.3	R hemiplegia	54	S, E, P	Iron	10.7
16	SS	2.7	L hand	127	S	Iron	13.3

Abbreviations: R, right; L, left; S, simple transfusions; E, erythrocytapheresis; P, partial exchange transfusions; AlloAb, erythrocyte alloantibodies; AutoAb, erythrocyte autoantibodies; DFO, deferoxamine; NC, noncompliance; SS, homozygous sickle cell anemia; SO_Arab, heterozygous HbS and HbO_Arab.

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