Single Locus Test for Hardy-Weinberg Equilibrium of Low-Affinity Fcγ Receptors: FcγRIIa, FcγRIIIa, and FcγRIIIb
| AA . | ||
|---|---|---|
| FcγRIIa . | FcγRIIIa . | FcγRIIIb . |
| Allele H = 0.47 | Allele V = 0.33 | Allele 1 = 0.4 |
| Allele R = 0.53 | Allele F = 0.67 | Allele 2 = 0.6 |
| Expected H/R = 0.50 | Expected V/F = 0.44 | Expected 1/2 = 0.48 |
| Observed H/R = 0.43 | Observed V/F = 0.50 | Observed 1/2 = 0.49 |
| χ2 = 3.31 | χ2 = 2.65 | χ2 = .02 |
| P = .07 | P = .10 | P > .10 |
| CA | ||
| FcγRIIa | FcγRIIIa | FcγRIIIb |
| Allele H = 0.53 | Allele V = 0.30 | Allele 1 = 0.33 |
| Allele R = 0.47 | Allele F = 0.70 | Allele 2 = 0.67 |
| Expected H/R = 0.50 | Expected V/F = 0.42 | Expected 1/2 = 0.44 |
| Observed H/R = 0.44 | Observed V/F = 0.39 | Observed 1/2 = 0.47 |
| χ2 = 2.89 | χ2 = .85 | χ2 = 1.01 |
| P = .09 | P > .10 | P > .10 |
| AA . | ||
|---|---|---|
| FcγRIIa . | FcγRIIIa . | FcγRIIIb . |
| Allele H = 0.47 | Allele V = 0.33 | Allele 1 = 0.4 |
| Allele R = 0.53 | Allele F = 0.67 | Allele 2 = 0.6 |
| Expected H/R = 0.50 | Expected V/F = 0.44 | Expected 1/2 = 0.48 |
| Observed H/R = 0.43 | Observed V/F = 0.50 | Observed 1/2 = 0.49 |
| χ2 = 3.31 | χ2 = 2.65 | χ2 = .02 |
| P = .07 | P = .10 | P > .10 |
| CA | ||
| FcγRIIa | FcγRIIIa | FcγRIIIb |
| Allele H = 0.53 | Allele V = 0.30 | Allele 1 = 0.33 |
| Allele R = 0.47 | Allele F = 0.70 | Allele 2 = 0.67 |
| Expected H/R = 0.50 | Expected V/F = 0.42 | Expected 1/2 = 0.44 |
| Observed H/R = 0.44 | Observed V/F = 0.39 | Observed 1/2 = 0.47 |
| χ2 = 2.89 | χ2 = .85 | χ2 = 1.01 |
| P = .09 | P > .10 | P > .10 |
Allele frequencies and the expected and observed frequency of heterozygotes are presented. Data were analyzed using χ2test for heterogeneity with 1 degree of freedom.