Table 2.

Anti-VEGF/VPF Treatment Suppresses the Growth of PEL Cells in SCID/beige Mice

Treatment No. of Mice Injected No. of Mice With Malignant Effusion
PBS  8  7 (88%)  
Antihuman VEGF/VPF Ab  9  0 (0%)  
Isotype control Ab  6 (100%) 
Treatment No. of Mice Injected No. of Mice With Malignant Effusion
PBS  8  7 (88%)  
Antihuman VEGF/VPF Ab  9  0 (0%)  
Isotype control Ab  6 (100%) 

Groups of mice were injected IP with BCBL-1 cells (1 × 107 cells/mouse) 1 day after γ-irradiation (400 rad). Mice received IP injections of PBS, antihuman VEGF/VPF Ab, or isotype control Ab twice weekly. Mice were killed 30 days later.

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