Table 2.

Clinical data in 10 CML patients treated with BMT

Patient No. Sex/Age at Diagnosis Gratwohl's Score Karyotype at Presentation [% Cell Ph+] Therapy Before BMT Duration of Follow-Up (mos) Duration of CCR (mos)
12  F/44  3  t(9;22)(q34;q11) [95%]  HU, IFN-α2b, Ara-c  32  4  
13  M/22  t(9;22)(q34;q11) [100%]  HU, splenectomy  56  65  
14 F/28  0  t(9;22)(q34;q11) [54%]  HU, IFN-α2a  95 36  
15  M/35  3  t(9;22)(q34;q11)del(7)(p11p21) [100%]  HU, IFN-α2b, Ara-c  37  12  
16  F/15  t(9;22)(q34;q11) [81%]  HU, IFN-α2a  40  24  
17 F/48  2  t(9;22)(q34;q11) [100%]  HU, IFN-α2b  47 24  
18  F/34  1  t(9;22)(q34;q11) [100%]  HU 76  60  
19  F/28  1  t(9;22)(q34;q11) [100%] HU  29  18  
20  M/13  2  t(9;22)(q34;q11) [100%]  HU, BU, IFN-α2b  84  44  
21  F/41  t(9;22)(q34;q11) [97%]  HU, IFN-α2b, Ara-c  47 24 
Patient No. Sex/Age at Diagnosis Gratwohl's Score Karyotype at Presentation [% Cell Ph+] Therapy Before BMT Duration of Follow-Up (mos) Duration of CCR (mos)
12  F/44  3  t(9;22)(q34;q11) [95%]  HU, IFN-α2b, Ara-c  32  4  
13  M/22  t(9;22)(q34;q11) [100%]  HU, splenectomy  56  65  
14 F/28  0  t(9;22)(q34;q11) [54%]  HU, IFN-α2a  95 36  
15  M/35  3  t(9;22)(q34;q11)del(7)(p11p21) [100%]  HU, IFN-α2b, Ara-c  37  12  
16  F/15  t(9;22)(q34;q11) [81%]  HU, IFN-α2a  40  24  
17 F/48  2  t(9;22)(q34;q11) [100%]  HU, IFN-α2b  47 24  
18  F/34  1  t(9;22)(q34;q11) [100%]  HU 76  60  
19  F/28  1  t(9;22)(q34;q11) [100%] HU  29  18  
20  M/13  2  t(9;22)(q34;q11) [100%]  HU, BU, IFN-α2b  84  44  
21  F/41  t(9;22)(q34;q11) [97%]  HU, IFN-α2b, Ara-c  47 24 

CML indicates chronic myeloid leukemia; BMT, bone marrow transplantation; HU, hydroxyurea; IFN, interferon; Ara-c, cytosine arabinoside; BU, busulfan; CCR, complete cytogenetic remission.

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