The effect of PAF on hemodynamic behavior of SS RBC in the mesocecum vasculature
Infusion . | No. . | PRU (mm Hg/mL/min/g) . | ΔPRU (%) . | Tpf (s) . | |
---|---|---|---|---|---|
Ringer . | RBC . | ||||
1. AA RBC | 4 | 4.0 ± 0.1 | 4.6 ± 0.1 | 15.0 ± 2.3 | 31.5 ± 1.9 |
2. PAF/AA RBC | 4 | 5.1 ± 0.7 | 6.0 ± 0.9 | 17.6 ± 1.7 | 37.0 ± 6.3 |
3. SS RBC | 4 | 4.2 ± 1.0 | 5.2 ± 1.3 | 25.2 ± 3.0* | 49.9 ± 2.3† |
4. PAF/SS RBC | 4 | 6.4 ± 1.9 | 9.0 ± 2.5 | 40.5 ± 6.7‡ | 90.8 ± 13.91-153 |
Infusion . | No. . | PRU (mm Hg/mL/min/g) . | ΔPRU (%) . | Tpf (s) . | |
---|---|---|---|---|---|
Ringer . | RBC . | ||||
1. AA RBC | 4 | 4.0 ± 0.1 | 4.6 ± 0.1 | 15.0 ± 2.3 | 31.5 ± 1.9 |
2. PAF/AA RBC | 4 | 5.1 ± 0.7 | 6.0 ± 0.9 | 17.6 ± 1.7 | 37.0 ± 6.3 |
3. SS RBC | 4 | 4.2 ± 1.0 | 5.2 ± 1.3 | 25.2 ± 3.0* | 49.9 ± 2.3† |
4. PAF/SS RBC | 4 | 6.4 ± 1.9 | 9.0 ± 2.5 | 40.5 ± 6.7‡ | 90.8 ± 13.91-153 |
Values are mean ± SD. In experiments using PAF, the vasculature was first pretreated with PAF (200 pg/mL) followed by a bolus infusion of SS RBC (Hct 30%, 0.2 mL).
Abbreviations: ΔPRU, PRU RBC/PRU Ringer; Tpf, pressure-flow recovery time to the baseline level.
P < .002 and
P < .0001, compared with respective values for AA RBC.
P < .024 and
P < .013, compared with respective values for SS RBC.