Percent inhibition by high molecular weight kininogen (Hk) peptides of recombinant fusion proteins of human umbilical vein endothelial cell proliferation
| Protein . | Domain . | Sequence . | Concentration of Peptide (μM) . | Proliferation % Inhibition . |
|---|---|---|---|---|
| HK | D3 | T255-Y280 | 139 | 0 |
| HK | D5 | GST-K420-S513 | 0.27* | 100* |
| HK | D6 | S565-P594 | 31.3 | 0 |
| Protein . | Domain . | Sequence . | Concentration of Peptide (μM) . | Proliferation % Inhibition . |
|---|---|---|---|---|
| HK | D3 | T255-Y280 | 139 | 0 |
| HK | D5 | GST-K420-S513 | 0.27* | 100* |
| HK | D6 | S565-P594 | 31.3 | 0 |
GST indicates glutathione-S-transferase fusion construct.
Only greater than 50% inhibition was considered significant.