Table 2.

Adhesion of GP Ib chimera-expressing CHO cells to vWf under flow

Cell Rolling*Rolling Velocity (μm/s)Saltatory Translocation*
Canine  −  −  −  
βIX  − −  −  
αβIX  +++   42 ± 1  +  
C35 ++  105 ± 4  ++  
C59  ++  110 ± 6  ++ 
C81  −  −  −  
C104  −  −  − 
C152  −  −  −  
C200  −  −  +++ 
C268  −  −  −  
C282  −  −  − 
H59  −  −  −  
H81  −  −  − 
H104  −  −  −  
H128  −  −  +++ 
H152  −  126 ± 7  +++  
H176  −  − 
Cell Rolling*Rolling Velocity (μm/s)Saltatory Translocation*
Canine  −  −  −  
βIX  − −  −  
αβIX  +++   42 ± 1  +  
C35 ++  105 ± 4  ++  
C59  ++  110 ± 6  ++ 
C81  −  −  −  
C104  −  −  − 
C152  −  −  −  
C200  −  −  +++ 
C268  −  −  −  
C282  −  −  − 
H59  −  −  −  
H81  −  −  − 
H104  −  −  −  
H128  −  −  +++ 
H152  −  126 ± 7  +++  
H176  −  − 
*

Grades are defined as follows: +, 1% to 10% of cells; ++, 11% to 79% of cells; +++, >80% of cells.

Mean ± SEM.

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