Comparison of day-15 marrow rating, day-15 MRD, and MRD-based risk groups with BFM risk groups
| BFM RG . | Marrow Rating . | Day-15 MRD . | MRD RG . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| M1 . | M2 . | M3 . | ≤ 10−4 . | 10−3 . | ≥ 10−2 . | LR . | IR . | HR . | |
| All patients/relapses | |||||||||
| SRG | 13/1 | 3/1 | 0/0 | 3/0 | 4/2 | 9/0 | 9/0 | 6/1 | 1/1 |
| MRD | 24/2 | 13/2 | 3/2 | 10/0 | 12/0 | 18/6 | 21/0 | 17/5 | 2/1 |
| HRG | 0/0 | 4/2 | 8/6 | 1/0 | 1/1 | 10/7 | 1/0 | 6/3 | 5/5 |
| Total | 37/3 | 20/5 | 11/8 | 14/0 | 17/3 | 37/13 | 31/0 | 29/9 | 8/7 |
| BFM RG . | Marrow Rating . | Day-15 MRD . | MRD RG . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| M1 . | M2 . | M3 . | ≤ 10−4 . | 10−3 . | ≥ 10−2 . | LR . | IR . | HR . | |
| All patients/relapses | |||||||||
| SRG | 13/1 | 3/1 | 0/0 | 3/0 | 4/2 | 9/0 | 9/0 | 6/1 | 1/1 |
| MRD | 24/2 | 13/2 | 3/2 | 10/0 | 12/0 | 18/6 | 21/0 | 17/5 | 2/1 |
| HRG | 0/0 | 4/2 | 8/6 | 1/0 | 1/1 | 10/7 | 1/0 | 6/3 | 5/5 |
| Total | 37/3 | 20/5 | 11/8 | 14/0 | 17/3 | 37/13 | 31/0 | 29/9 | 8/7 |
MRD RG, MRD-based risk groups; LR, low risk; IR, intermediate risk; HR, high risk; BFM RG, BFM risk groups; SRG, standard-risk group; MRG, medium-risk group; HRG, high-risk group.