Summary of clinicopathologic data, MSI status of patients with E2F4 mutations
Patient No. . | Diagnosis . | MSI Status . | Mutational Analysis . | ||||
---|---|---|---|---|---|---|---|
E2F4 (AGC) 13* . | TGF-βRII (A) 10 . | BAX (G) 8 . | IGFIIR (G) 8 . | hMSH3 (A) 8 . | |||
54 | T-ALL | + | Deletion (7) | N | N | N | N |
6 | Acute ATL | + | Insertion (16) | N | N | N | N |
18 | Acute ATL | ++ | Insertion (16) | N | N | N | N |
Patient No. . | Diagnosis . | MSI Status . | Mutational Analysis . | ||||
---|---|---|---|---|---|---|---|
E2F4 (AGC) 13* . | TGF-βRII (A) 10 . | BAX (G) 8 . | IGFIIR (G) 8 . | hMSH3 (A) 8 . | |||
54 | T-ALL | + | Deletion (7) | N | N | N | N |
6 | Acute ATL | + | Insertion (16) | N | N | N | N |
18 | Acute ATL | ++ | Insertion (16) | N | N | N | N |
MSI indicates microsatellite instability; +, MSI at 1 locus; ++, MSI at 2 loci; N, negative for mutation.
The number in parentheses on the E2F4 gene indicates total number of AGC repeats observed in the E2F4 gene in each of the samples.