Table 1.

Summary of clinicopathologic data, MSI status of patients with E2F4 mutations

Patient No. Diagnosis MSI Status Mutational Analysis
E2F4 (AGC) 13*TGF-βRII (A) 10 BAX (G) 8 IGFIIR (G) 8 hMSH3 (A) 8
54 T-ALL  +  Deletion (7)  N  N  N  N  
Acute ATL  +  Insertion (16)  N  N  N  N  
18 Acute ATL  ++  Insertion (16)  N  N  N  
Patient No. Diagnosis MSI Status Mutational Analysis
E2F4 (AGC) 13*TGF-βRII (A) 10 BAX (G) 8 IGFIIR (G) 8 hMSH3 (A) 8
54 T-ALL  +  Deletion (7)  N  N  N  N  
Acute ATL  +  Insertion (16)  N  N  N  N  
18 Acute ATL  ++  Insertion (16)  N  N  N  

MSI indicates microsatellite instability; +, MSI at 1 locus; ++, MSI at 2 loci; N, negative for mutation.

*

The number in parentheses on the E2F4 gene indicates total number of AGC repeats observed in the E2F4 gene in each of the samples.

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