Clinical and biological characteristics of MALT lymphoma patients according to the stage of the disease
| . | All Patients . | Stage I-II . | Stage III-IV . | |||
|---|---|---|---|---|---|---|
| n . | (%) . | n . | (%) . | n . | (%) . | |
| Total | 158 | (100) | 104 | (66) | 54 | (34) |
| Sex | ||||||
| Male | 76 | (48) | 54 | (52) | 22 | (41) |
| Female | 82 | (52) | 51 | (48) | 31 | (59) |
| Age (years) | ||||||
| Less than 65 | 111 | (70) | 78 | (75) | 33 | (61) |
| At least 65 | 47 | (30) | 26 | (35) | 21 | (39) |
| Performance status (ECOG) | ||||||
| 0-1 | 63 | (97) | 33 | (97) | 30 | (97) |
| > 2 | 2 | (3) | 1 | (3) | 1 | (3) |
| B symptoms | ||||||
| Absent | 135 | (85) | 92 | (88) | 43 | (80) |
| Present | 23 | (14) | 12 | (12) | 11 | (20) |
| Bone marrow involvement | 31 | (20) | 0 | — | 31 | (58) |
| Spleen involvement | 13 | (8) | 1* | (1) | 12 | (22) |
| Liver involvement | 7 | (4) | 0 | — | 7 | (13) |
| Extra nodal involvement | ||||||
| 1 | 116 | (75) | 103 | (99) | 12 | (23) |
| At least 2 | 42 | (25) | 1† | (1) | 42 | (77) |
| Hb less than 12 g/dL | 24 | (21) | 10 | (10) | 14 | (26) |
| LDH greater than normal | 9 | (6.5) | 5 | (5) | 4 | (7) |
| β2-microglobuline greater than 3 mg/L | 20 | (22) | 4 | (4) | 16 | (30) |
| . | All Patients . | Stage I-II . | Stage III-IV . | |||
|---|---|---|---|---|---|---|
| n . | (%) . | n . | (%) . | n . | (%) . | |
| Total | 158 | (100) | 104 | (66) | 54 | (34) |
| Sex | ||||||
| Male | 76 | (48) | 54 | (52) | 22 | (41) |
| Female | 82 | (52) | 51 | (48) | 31 | (59) |
| Age (years) | ||||||
| Less than 65 | 111 | (70) | 78 | (75) | 33 | (61) |
| At least 65 | 47 | (30) | 26 | (35) | 21 | (39) |
| Performance status (ECOG) | ||||||
| 0-1 | 63 | (97) | 33 | (97) | 30 | (97) |
| > 2 | 2 | (3) | 1 | (3) | 1 | (3) |
| B symptoms | ||||||
| Absent | 135 | (85) | 92 | (88) | 43 | (80) |
| Present | 23 | (14) | 12 | (12) | 11 | (20) |
| Bone marrow involvement | 31 | (20) | 0 | — | 31 | (58) |
| Spleen involvement | 13 | (8) | 1* | (1) | 12 | (22) |
| Liver involvement | 7 | (4) | 0 | — | 7 | (13) |
| Extra nodal involvement | ||||||
| 1 | 116 | (75) | 103 | (99) | 12 | (23) |
| At least 2 | 42 | (25) | 1† | (1) | 42 | (77) |
| Hb less than 12 g/dL | 24 | (21) | 10 | (10) | 14 | (26) |
| LDH greater than normal | 9 | (6.5) | 5 | (5) | 4 | (7) |
| β2-microglobuline greater than 3 mg/L | 20 | (22) | 4 | (4) | 16 | (30) |
This patient presented with gastric MALT lymphoma with histologically involved mesenteric lymph nodes and splenomegaly without histologically proven involvement. This patient was considered as having a stage II disease.
This patient presented with gastric localized MALT lymphoma, but the histologic analysis of systematic hepatic biopsy made during the gastrectomy reported a suspicious infiltration of small lymphocytes with cellular atypia. This patient did not present any sign of clinical or biological liver disease during the evolution and then was considered as having a localized disease with 2 involved extranodal sites: stomach and suspected liver.