RARm4 transgenic mice
| Founder . | Transgene Expression in Bone Marrow . | Cohort . |
|---|---|---|
| 4142 | ++ | 26 mice. 10-18 mo |
| 4151 | + | 10 mice. 10-18 mo |
| 4155 | ND | Founder, 13 mo |
| No offspring. | ||
| 4157 | +/− | Founder, 9 months* |
| 4159 | + | 2 mice, 11 & 18 mo |
| 4160 | − | Founder, 9 mo* |
| 4192 | ++ | 5 mice, 10-18 mo |
| 4195 | − | Founder, 9 mo* |
| Founder . | Transgene Expression in Bone Marrow . | Cohort . |
|---|---|---|
| 4142 | ++ | 26 mice. 10-18 mo |
| 4151 | + | 10 mice. 10-18 mo |
| 4155 | ND | Founder, 13 mo |
| No offspring. | ||
| 4157 | +/− | Founder, 9 months* |
| 4159 | + | 2 mice, 11 & 18 mo |
| 4160 | − | Founder, 9 mo* |
| 4192 | ++ | 5 mice, 10-18 mo |
| 4195 | − | Founder, 9 mo* |
See note to Table 1.
Founders 4157, 4160, and 4195 (and their offspring) were monitored for illness for up to 9 months. Monitoring was then discontinued given very low to absent transgene expression.
ND: not determined.