PMLRARm4 leukemias bone marrow
| Mice . | Blast + Pro . | Imm Neut . | Mat Neut . | Erythroid . | Lymph . | Eosin . |
|---|---|---|---|---|---|---|
| Control | 2.0 ± 0.7 | 16.4 ± 2.4 | 27.0 ± 5.0 | 40.3 ± 6.5 | 12.1 ± 1.9 | 2.3 ± 0.9 |
| PR | 81.3 ± 8.1 | 4.5 ± 2.6 | 0.7 ± 0.7 | 8.7 ± 7.7 | 4.5 ± 2.2 | 0.3 ± 0.3 |
| PRm4 | 65.7 ± 27.1 | 13.1 ± 14.4 | 12.7 ± 17.5 | 3.5 ± 2.4 | 4.4 ± 2.4 | 0.5 ± 1.1 |
| Leukemia | ||||||
| 4042 | 44.5 | 37.5 | 5.5 | 4 | 6 | 2.5 |
| 4048.3 | 66.5 | 11 | 15.5 | 0.5 | 6.5 | 0 |
| 4048.5 | 94.5 | 0.5 | 0 | 3.5 | 1.5 | 0 |
| 4099 | 90 | 4.5 | 0.5 | 2.5 | 2 | 0 |
| 4104 | 33 | 12 | 42 | 7 | 6 | 0 |
| Mice . | Blast + Pro . | Imm Neut . | Mat Neut . | Erythroid . | Lymph . | Eosin . |
|---|---|---|---|---|---|---|
| Control | 2.0 ± 0.7 | 16.4 ± 2.4 | 27.0 ± 5.0 | 40.3 ± 6.5 | 12.1 ± 1.9 | 2.3 ± 0.9 |
| PR | 81.3 ± 8.1 | 4.5 ± 2.6 | 0.7 ± 0.7 | 8.7 ± 7.7 | 4.5 ± 2.2 | 0.3 ± 0.3 |
| PRm4 | 65.7 ± 27.1 | 13.1 ± 14.4 | 12.7 ± 17.5 | 3.5 ± 2.4 | 4.4 ± 2.4 | 0.5 ± 1.1 |
| Leukemia | ||||||
| 4042 | 44.5 | 37.5 | 5.5 | 4 | 6 | 2.5 |
| 4048.3 | 66.5 | 11 | 15.5 | 0.5 | 6.5 | 0 |
| 4048.5 | 94.5 | 0.5 | 0 | 3.5 | 1.5 | 0 |
| 4099 | 90 | 4.5 | 0.5 | 2.5 | 2 | 0 |
| 4104 | 33 | 12 | 42 | 7 | 6 | 0 |
Data are shown as arithmetic means ± SD. Percentages of nucleated cells were derived from 400 cell differential counts of Wright's Giemsa stained bone marrow smears. Abbreviations: see legend to Table 3. Control n = 6, PR (MRP8-PMLRARα) primary leukemias n = 6, PRm4 (MRP8-PMLRARαm4) primary leukemias n = 5. Bone marrow smears were not available for leukemic mice 4048.2 and 4048.4.