Liver biopsy findings in 84 patients with PCT
| Stage . | HCV+ . | HCV− . | Not Tested for HCV . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N . | NIF . | HPCSI . | EtOH . | n . | NIF . | HPCSI . | EtOH . | n . | NIF . | HPCSI . | EtOH . | |
| 0 | 12 | 10 | 1.8 | 2.6 | 17 | 4 | 1.9 | 1.2 | 14 | 2 | 1.7 | 1.7 |
| 1 | 7 | 6 | 1.7 | 2.6 | 1 | 1 | 3.0 | 2.0 | 1 | 0 | 3.0 | 2.0 |
| 2 | 14 | 14 | 1.8 | 2.7 | 2 | 2 | 1.5 | 0.5 | 5 | 4 | 1.4 | 2.2 |
| 3 | 3 | 3 | 2.7 | 3.0 | — | — | — | — | 2 | 2 | 2.0 | 3.0 |
| 4 | 3 | 3 | 2.6 | 3.0 | — | — | — | — | 3 | 2 | 2.7 | 2.7 |
| Stage . | HCV+ . | HCV− . | Not Tested for HCV . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N . | NIF . | HPCSI . | EtOH . | n . | NIF . | HPCSI . | EtOH . | n . | NIF . | HPCSI . | EtOH . | |
| 0 | 12 | 10 | 1.8 | 2.6 | 17 | 4 | 1.9 | 1.2 | 14 | 2 | 1.7 | 1.7 |
| 1 | 7 | 6 | 1.7 | 2.6 | 1 | 1 | 3.0 | 2.0 | 1 | 0 | 3.0 | 2.0 |
| 2 | 14 | 14 | 1.8 | 2.7 | 2 | 2 | 1.5 | 0.5 | 5 | 4 | 1.4 | 2.2 |
| 3 | 3 | 3 | 2.7 | 3.0 | — | — | — | — | 2 | 2 | 2.0 | 3.0 |
| 4 | 3 | 3 | 2.6 | 3.0 | — | — | — | — | 3 | 2 | 2.7 | 2.7 |
NIF indicates the number of patients with a necroinflammatory process of grade 1 or higher. Mean HPCSI scores range from 0-4.25 EtOH indicates the mean score of alcohol consumption by grade. Grades range from 0-3, as described in “Materials and Methods.” Anti-HCV IgG was serologically detected by ELISA, as described in “Materials and Methods.” Histologic grading and staging of HCV was performed by the method of Batts and Ludwig.26 Grading is a measure of the severity of the necroinflammatory process, with grade 0 indicating normal. Staging refers to the degree of fibrosis present, with stage 0 indicating normal.