Expression data from transgenic mice carrying the wild-type and mutant forms of the EKLF promoter
| Construct/Line . | . | Normalized CAT Values . | Copy Number . | |
|---|---|---|---|---|
| F0 . | F1 . | |||
| 1150 EKLFCAT | 24 | 0.5 | 5 | |
| 26 | 10 | 4.3 | 7 | |
| 29 | 32 | 18 | 2 | |
| 33 | 20 | 15 | 1 | |
| 1150 (GEMG) | 7.1 | <0.1 | <0.1 | 3 |
| 7.2 | <0.1 | ND | 1 | |
| 7.4 | 98 | 98 | 6 | |
| 8.2 | <0.1 | <0.1 | 2 | |
| 9.1 | <0.1 | <0.1 | 1 | |
| 9.4 | <0.1 | ND | 5 | |
| 19.1 | <0.1 | ND | 3 | |
| 19.7 | <0.1 | <0.1 | 5 | |
| 19.8 | <0.1 | <0.1 | 1 | |
| 20.3 | <0.1 | ND | 7 | |
| 20.5 | <0.1 | <0.1 | 3 | |
| 46 | 46 | 92 | 5 | |
| 58 | <0.1 | <0.1 | 3 | |
| 69 | <0.1 | <0.1 | 3 | |
| 1150 (GMEGM) | 11.1 | <0.1 | <0.1 | 1 |
| 11.4 | <0.1 | <0.1 | 3 | |
| 11.5 | <0.1 | <0.1 | 6 | |
| 12.1 | <0.1 | <0.1 | 4 | |
| 12.5 | <0.1 | <0.1 | 4 | |
| 15.4 | <0.1 | <0.1 | 3 | |
| 15.5 | <0.1 | <0.1 | 22 | |
| 16.1 | <0.1 | <0.1 | 6 | |
| 17.5 | <0.1 | <0.1 | 20 | |
| 17.7 | 96 | ND | 18 | |
| 17.8 | <0.1 | <0.1 | 20 | |
| 21.2 | <0.1 | <0.1 | 2 | |
| 1150 (GMEMGM) | 41 | <0.1 | <0.1 | 14 |
| 44 | <0.1 | <0.1 | 1 | |
| Construct/Line . | . | Normalized CAT Values . | Copy Number . | |
|---|---|---|---|---|
| F0 . | F1 . | |||
| 1150 EKLFCAT | 24 | 0.5 | 5 | |
| 26 | 10 | 4.3 | 7 | |
| 29 | 32 | 18 | 2 | |
| 33 | 20 | 15 | 1 | |
| 1150 (GEMG) | 7.1 | <0.1 | <0.1 | 3 |
| 7.2 | <0.1 | ND | 1 | |
| 7.4 | 98 | 98 | 6 | |
| 8.2 | <0.1 | <0.1 | 2 | |
| 9.1 | <0.1 | <0.1 | 1 | |
| 9.4 | <0.1 | ND | 5 | |
| 19.1 | <0.1 | ND | 3 | |
| 19.7 | <0.1 | <0.1 | 5 | |
| 19.8 | <0.1 | <0.1 | 1 | |
| 20.3 | <0.1 | ND | 7 | |
| 20.5 | <0.1 | <0.1 | 3 | |
| 46 | 46 | 92 | 5 | |
| 58 | <0.1 | <0.1 | 3 | |
| 69 | <0.1 | <0.1 | 3 | |
| 1150 (GMEGM) | 11.1 | <0.1 | <0.1 | 1 |
| 11.4 | <0.1 | <0.1 | 3 | |
| 11.5 | <0.1 | <0.1 | 6 | |
| 12.1 | <0.1 | <0.1 | 4 | |
| 12.5 | <0.1 | <0.1 | 4 | |
| 15.4 | <0.1 | <0.1 | 3 | |
| 15.5 | <0.1 | <0.1 | 22 | |
| 16.1 | <0.1 | <0.1 | 6 | |
| 17.5 | <0.1 | <0.1 | 20 | |
| 17.7 | 96 | ND | 18 | |
| 17.8 | <0.1 | <0.1 | 20 | |
| 21.2 | <0.1 | <0.1 | 2 | |
| 1150 (GMEMGM) | 41 | <0.1 | <0.1 | 14 |
| 44 | <0.1 | <0.1 | 1 | |
CAT values are expressed as the percentage conversion of substrate to product, normalized for the amount of protein in each sample.