Table 3. Karyotypic analysis and... | American Society of Hematology

Table 3.

Karyotypic analysis and detection of fusion transcripts by reverse transcriptase-polymerase chain reaction in bone marrow or peripheral blood from patients with adult or childhood acute leukemias with and without p15 methylation at diagnosis

	Normal Karyotype			Hyperdiploidies ≥51 Chromosomes		Chromosomal Deletions			Chromosomal Inversions		Chromosomal Translocations		Karyotyping Not Done
	ALL (n = 6)	AML (n = 4)	ABL (n = 1)	ALL (n = 12)	AML (n = 1)	ALL (n = 1)	AML (n = 1)	ABL (n = 1)	ALL (n = 1)	AML (n = 1)	ALL (n = 4)	AML (n = 2)	AML (n = 2)^3-150
p15 methylation	2	4	0	4	0	1	0	1	0	1	3^3-151	2	1
No p15 methylation	4	0	1	8	1	0	1	0	1	0	1^3-152	0	1

	Normal Karyotype			Hyperdiploidies ≥51 Chromosomes		Chromosomal Deletions			Chromosomal Inversions		Chromosomal Translocations		Karyotyping Not Done
	ALL (n = 6)	AML (n = 4)	ABL (n = 1)	ALL (n = 12)	AML (n = 1)	ALL (n = 1)	AML (n = 1)	ABL (n = 1)	ALL (n = 1)	AML (n = 1)	ALL (n = 4)	AML (n = 2)	AML (n = 2)^3-150
p15 methylation	2	4	0	4	0	1	0	1	0	1	3^3-151	2	1
No p15 methylation	4	0	1	8	1	0	1	0	1	0	1^3-152	0	1

F3-150

Both patients had AML1-ETO fusion transcripts.

F3-151

One of the 3 patients had mBCR-ABL fusion transcripts.

F3-152

The patient had AF4-MLL fusion transcripts.

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