Table 3. Pulmonary function after... | American Society of Hematology

Table 3.

Pulmonary function after transplantation for sickle cell disease

Patient No.	Indication for BMT	Baseline PFTs	1 y post-BMT	2 y post-BMT	3 y post-BMT	≥4 y post-BMT
1	Stroke	Mild to mod RPD	—	—	Mild RPD	Mild to mod RPD
2	Stroke	Normal	—	—	Normal
3	Stroke	—	Mild to mod RPD
5	ACS, TIAs	Mild RPD	Mild to mod RPD
6	ACS & abnl MRI	Normal	Normal	Normal	—	Normal
7	Stroke	—	—	—	Normal	Normal
8	ACS	Mild RPD	Mild RPD	Mild RPD	Mild RPD	Mild RPD
10	VOC/abnl TCD	Mild RPD	Mild RPD	Mild RPD
11	VOC/stroke	Mild RPD	Mild RPD	Mild RPD
12	ACS	—	—	Normal	—	Normal
13	Stroke	Normal
14	Stroke	Normal	Normal	Normal
15	Stroke	Normal	Normal	Normal	Normal
16	VOC	Normal	Normal	Mild RPD	Mild RPD
17	Stroke	Too young	—	Normal
18	ACS, abnl MRI	Mild RPD	Mild RPD	Mild RPD	Mild to mod RPD	Mild RPD
19	Stroke	Mod RPD	—	—	—	Normal
20	Stroke	Mild RPD	Mild RPD	Mild RPD
21	VOC	Normal	Normal	Normal	Normal	Normal
22	VOC	Normal	—
23	Stroke	Mild RPD	—	Mild RPD
24	ACS	Too young	—	Normal
25	VOC	Mild RPD	Normal
26	ACS, abnl MRI	Normal	—	Normal
27	ACS, abnl MRI	Mild RPD	Normal	Mild RPD/mild OPD
28	Stroke	Normal	Normal

Patient No.	Indication for BMT	Baseline PFTs	1 y post-BMT	2 y post-BMT	3 y post-BMT	≥4 y post-BMT
1	Stroke	Mild to mod RPD	—	—	Mild RPD	Mild to mod RPD
2	Stroke	Normal	—	—	Normal
3	Stroke	—	Mild to mod RPD
5	ACS, TIAs	Mild RPD	Mild to mod RPD
6	ACS & abnl MRI	Normal	Normal	Normal	—	Normal
7	Stroke	—	—	—	Normal	Normal
8	ACS	Mild RPD	Mild RPD	Mild RPD	Mild RPD	Mild RPD
10	VOC/abnl TCD	Mild RPD	Mild RPD	Mild RPD
11	VOC/stroke	Mild RPD	Mild RPD	Mild RPD
12	ACS	—	—	Normal	—	Normal
13	Stroke	Normal
14	Stroke	Normal	Normal	Normal
15	Stroke	Normal	Normal	Normal	Normal
16	VOC	Normal	Normal	Mild RPD	Mild RPD
17	Stroke	Too young	—	Normal
18	ACS, abnl MRI	Mild RPD	Mild RPD	Mild RPD	Mild to mod RPD	Mild RPD
19	Stroke	Mod RPD	—	—	—	Normal
20	Stroke	Mild RPD	Mild RPD	Mild RPD
21	VOC	Normal	Normal	Normal	Normal	Normal
22	VOC	Normal	—
23	Stroke	Mild RPD	—	Mild RPD
24	ACS	Too young	—	Normal
25	VOC	Mild RPD	Normal
26	ACS, abnl MRI	Normal	—	Normal
27	ACS, abnl MRI	Mild RPD	Normal	Mild RPD/mild OPD
28	Stroke	Normal	Normal

Abnl = abnormal; ACS = acute chest syndrome; BMT = bone marrow transplantation; OPD = obstructive pulmonary disease; RPD = restrictive pulmonary disease; TCD = transcranial Doppler; TIA = transient ischemic attack; VOC = vaso-occlusive crisis.

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